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Association between fine particulate matter and atrial fibrillation in implantable cardioverter defibrillator patients: a systematic review and meta-analysis

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Abstract

Purpose

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia with several risk factors. Recent studies have suggested that the exposure to fine particulate matter (PM2.5) increased the incidence of AF, but there is no meta-analysis of AF occurrence due to the exposure to PM2.5 in implantable cardioverter defibrillator (ICD) patients.

Methods

We conducted a systematic review of publication using PubMed, Embase, the Cochrane library, and Web of Science to explore the association between PM2.5 and AF within ICD patients. The chosen studies were published until June 11, 2020. The I2 statistic and Q test were used to examine statistical heterogeneity across studies. Further sensitivity analyses were carried out to ascertain the reason for heterogeneity. Fixed or random-effect model was used to combine the effects. Final result was presented as the OR with 95% CI of increased incidence of AF for every 10 μg/m3 PM2.5 concentration increased.

Results

After screening our analysis contained four studies and involved 1689 AF events from 572 patients. After using the random-effect model to combine the included study result, the overall OR was 1.24 (95% CI 1.00–1.53).

Conclusion

Our meta-analysis indicated that PM2.5 exposure had an adverse effect on AF incidence in ICD patients.

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Funding

This work was supported by the Clinical Characteristic Application Research Project of Capital Beijing (Z181100001718055).

Author information

Authors and Affiliations

  1. Department of Thoracic Surgery, Beijing Aerospace General Hospital, Wanyuan North Road, Beijing, 100076, China

    Chao Yue, Fengwei Li & Yingtai Chen

  2. Department of Thoracic Surgery, Peking University People’s Hospital, Xizhimen South Street, Beijing, 100044, China

    Chao Yue, Fengwei Li & Yingtai Chen

  3. Department of Pediatric Intensive Care Unit, Chinese Academy of Medical Sciences and Peking Union Medical College Fuwai Hospital, North Lishi Road, Beijing, 100037, China

    Fan Yang

  4. Peking Union Medical College, Chinese Academy of Medical Sciences, Dongdan 3rd, Beijing, ,100730, China

    Luyi Wang

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  1. Chao Yue
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Contributions

Chao Yue conceived and designed the work and took part in every step of the work, including publication screening, statistical analysis, and writing of the manuscript. Fan Yang participated in the publication screening and analysis. Luyi Wang participated in data analysis and writing of the manuscript. Fengwei Li reviewed the screening and critiqued the manuscript. Yingtai Chen was responsible for the conception of the manuscript, reviewing, and critique of the manuscript.

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Correspondence to Chao Yue.

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Yue, C., Yang, F., Wang, L. et al. Association between fine particulate matter and atrial fibrillation in implantable cardioverter defibrillator patients: a systematic review and meta-analysis. J Interv Card Electrophysiol 59, 595–601 (2020). https://doi.org/10.1007/s10840-020-00864-1

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  • DOI: https://doi.org/10.1007/s10840-020-00864-1

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