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Atrial fibrillation and conduction system disease: the roles of catheter ablation and permanent pacing

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Journal of Interventional Cardiac Electrophysiology Aims and scope Submit manuscript

Abstract

Atrial fibrillation (AF) and diseases of the cardiac conduction system frequently co-exist, and interactions between these rhythm disturbances can adversely impact patient outcomes. Concurrent AF and sinus node disease often manifests as the tachy-brady syndrome wherein the underlying sinus node dysfunction can pose a challenge to AF management. Similarly, the combination of AF and left bundle branch block increases mortality in individuals with co-existent heart failure and hampers effective delivery of cardiac resynchronization therapy. A thorough understanding of the therapeutic interventions available for these conditions, including the role of catheter ablation and permanent pacemaker programming, is crucial for optimal management in affected patients.

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Funding

Dr. Lau is supported by the Robert J. Craig Lectureship from the University of Adelaide. Dr. Sanders is supported by Practitioner Fellowships from the National Health and Medical Research Council of Australia and the National Heart Foundation of Australia.

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Authors and Affiliations

  1. Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia

    Anand Thiyagarajah, Dennis H. Lau & Prashanthan Sanders

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  1. Anand Thiyagarajah
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  2. Dennis H. Lau
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  3. Prashanthan Sanders
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Correspondence to Prashanthan Sanders.

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Conflict of interest

Dr. Sanders reports having served on the advisory board of Biosense-Webster, Medtronic, Abbott, Boston Scientific, and CathRx. Dr. Sanders reports that the University of Adelaide receives on his behalf lecture and/or consulting fees from Biosense-Webster, Medtronic, Abbott, and Boston Scientific. Dr. Sanders reports that the University of Adelaide receives on his behalf research funding from Medtronic, Abbott, Boston Scientific, Biotronik, and Liva Nova.

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Thiyagarajah, A., Lau, D.H. & Sanders, P. Atrial fibrillation and conduction system disease: the roles of catheter ablation and permanent pacing. J Interv Card Electrophysiol 52, 395–402 (2018). https://doi.org/10.1007/s10840-018-0429-9

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  • DOI: https://doi.org/10.1007/s10840-018-0429-9

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