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Cryoballoon ablation for pulmonary vein isolation in patients with atrial fibrillation: preliminary results using novel short-tip cryoballoon

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Journal of Interventional Cardiac Electrophysiology Aims and scope Submit manuscript

Abstract

Purpose

In this study, we aimed to report our preliminary experience regarding the impact of the novel short-tip (ST) cryoballoon (CB) on procedural efficacy and signal quality during pulmonary vein (PV) isolation for both paroxysmal and persistent atrial fibrillation.

Methods

Between March, 2015, and August, 2015, we enrolled a total of 64 patients (47 patients male, 73 %) with a mean age of 60 ± 11 years. In the study population, 31 patients (48 %) underwent PVI using Advance (ADV) CB and 33 (52 %) patients with ST CB. In all patients, a 28-mm balloon was used.

Results

Acute procedural success rates were 100 % for the entire study population. A statistically insignificant increase in the percentage of PV signal recordings was observed with ST CB in all PVs compared to ADV CB [88 vs. 81 % for left superior PV (LSPV), 82 vs. 78 % for left inferior PV (LIPV), 85 vs. 84 % for right superior PV (RSPV), 82 vs. 71 % for right inferior PV (RIPV), p < 0.05]. Additionally, the difference in minimum temperature reached during the procedure per PV was not statistically significant between ST CB and ADV CB except the LIPV (LSPV −44.2 ± 5.9 vs. −45.6 ± 5.3 °C, p = 0.970; LIPV −38.7 ± 4.6 °C vs −44.6 ± 6.8 °C, p < 0.001; RSPV −45.6 ± 7.4 °C vs.−47.2 ± 6.1 °C, p = 0.168; RIPV −41.4 ± 5.1 °C vs.−43.7 ± 6.3 °C, p = 0.360). Time to isolation for each PV was similar between ST and ADV CB (p > 0.05).

Conclusion

Our preliminary findings indicated similar acute procedural success for the novel ST CB compared with second generation ADV CB. The increase in the ratio of PV signal recordings obtained during the PVI using the novel ST CB was not significant.

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Authors and Affiliations

  1. Krankenhaus Porz am Rhein, Department of Cardiology/Electrophysiology, Witten/Herdecke University, Cologne, Germany

    Buelent Koektuerk, Hikmet Yorgun, Cem H. Turan, Muhammet Necati Murat Aksoy, Ramazan G. Turan, Eduard Gorr, Christian Hoppe & Marc Horlitz

  2. Klinikum Lüdenscheid Klinik für Innere Medizin V, Lüdenscheid, Germany

    Oezlem Koektuerk

  3. Krankenhaus Porz am Rhein, Department of Radiology, Witten/Herdecke University, Cologne, Germany

    Paul M. Bansmann

Authors
  1. Buelent Koektuerk
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  2. Hikmet Yorgun
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  3. Oezlem Koektuerk
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  4. Cem H. Turan
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  5. Muhammet Necati Murat Aksoy
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  6. Ramazan G. Turan
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  7. Eduard Gorr
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  8. Paul M. Bansmann
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  9. Christian Hoppe
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  10. Marc Horlitz
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Corresponding author

Correspondence to Buelent Koektuerk.

Ethics declarations

The study was in compliance with the principles outlined in the Declaration of Helsinki and approved by the Institutional Ethics Committee.

Conflict of Interest

Dr. Buelent Koektuerk is the consultant of Medtronic Company. Other authors did not have any conflict of interest.

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Koektuerk, B., Yorgun, H., Koektuerk, O. et al. Cryoballoon ablation for pulmonary vein isolation in patients with atrial fibrillation: preliminary results using novel short-tip cryoballoon. J Interv Card Electrophysiol 47, 91–98 (2016). https://doi.org/10.1007/s10840-016-0134-5

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  • DOI: https://doi.org/10.1007/s10840-016-0134-5

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