Skip to main content
Log in

Abstract

The incidence and prevalence of atrial fibrillation (AF) increase progressively with age, and approximately 50% of patients with AF are 75 years of age or older. Advanced age is also a potent risk factor for stroke in patients with AF, and the proportion of strokes attributable to AF increases exponentially with age. In addition, AF contributes incrementally to health care utilization and costs, and decrementally to survival and quality of life in older adults. Furthermore, the societal impact of AF will likely double over the next three decades due to the aging of the population. For these reasons, it is essential to develop more effective strategies for the prevention and treatment of AF in older individuals.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9

Similar content being viewed by others

References

  1. Go, A. S., Hylek, E. M., Phillips, K. A., Chang, Y., Henault, L. E., Selby, J. V., & Singer, D. E. (2001). Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and risk factors in atrial fibrillation (ATRIA) study. Journal of the American Medical Association, 285, 2370–2375.

    Article  PubMed  CAS  Google Scholar 

  2. Rosamond, W., Flegal, K., Friday, G., et al. (2007). Heart disease and stroke statistics—2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation, 115, e69–e171.

    Article  PubMed  Google Scholar 

  3. Wattigney, W. A., Mensah, G. A., & Croft, J. B. (2003). Increasing trends in hospitalization for atrial fibrillation in the United States, 1985 through 1999: implications for primary prevention. Circulation, 108, 711–716.

    Article  PubMed  Google Scholar 

  4. Coyne, K. S., Paramore, C., Grandy, S., Mercader, M., Reynolds, M., & Zimetbaum, P. (2006). Assessing the direct costs of treating nonvalvular atrial fibrillation in the United States. Value in Health, 9, 348–356.

    Article  PubMed  Google Scholar 

  5. Wolf, P. A., Mitchell, J. B., Baker, C. S., Kannel, W. B., & D’Agostino, R. B. (1998). Impact of atrial fibrillation on mortality, stroke, and medical costs. Archives of Internal Medicine, 158, 229–234.

    Article  PubMed  CAS  Google Scholar 

  6. Psaty, B. M., Manolio, T. A., Kuller, L. H., et al. (1997). Incidence of and risk factors for atrial fibrillation in older adults. Circulation, 96, 2455–2461.

    PubMed  CAS  Google Scholar 

  7. Miyasaka, Y., Barnes, M. E., Gersh, B. J., et al. (2006). Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980–2000, and implications on the projections for future prevalence. Circulation, 114, 119–125.

    Article  PubMed  Google Scholar 

  8. Feinberg, W. M., Blackshear, J. L., Laupacis, A., Kronmal, R., & Hart, R. G. (1995). Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications. Archives of Internal Medicine, 155, 469–473.

    Article  PubMed  CAS  Google Scholar 

  9. Benjamin, E. J., Levy, D., Vaziri, S. M., D’Agostino, R. B., Belanger, A. J., & Wolf, P. A. (1994). Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study. Journal of the American Medical Association, 271, 840–844.

    Article  PubMed  CAS  Google Scholar 

  10. Vaziri, S. M., Larson, M. G., Benjamin, E. J., & Levy, D. (1994). Echocardiographic predictors of nonrheumatic atrial fibrillation. The Framingham Heart Study. Circulation, 89, 724–730.

    PubMed  CAS  Google Scholar 

  11. Djousse, L., Levy, D., Benjamin, E. J., et al. (2004). Long-term alcohol consumption and the risk of atrial fibrillation in the Framingham Study. The American Journal of Cardiology, 93, 710–713.

    Article  PubMed  CAS  Google Scholar 

  12. Chen, L. Y., & Shen, W. K. (2007). Epidemiology of atrial fibrillation: a current perspective. Heart Rhythm, 4(Suppl 3), S1–S6.

    Article  PubMed  Google Scholar 

  13. Lakatta, E., & Levy, D. (2003). Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: part I: aging arteries: a “set up” for vascular disease. Circulation, 107, 139–146.

    Article  PubMed  Google Scholar 

  14. Lakatta, E. G., & Levy, D. (2003). Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: part II: the aging heart in health: links to heart disease. Circulation, 107, 346–354.

    Article  PubMed  Google Scholar 

  15. Lakatta, E. G. (2003). Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: part III: cellular and molecular clues to heart and arterial aging. Circulation, 107, 490–497.

    Article  PubMed  Google Scholar 

  16. Anonymous (1994) Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation. Analysis of pooled data from five randomized controlled trials. Archives of Internal Medicine, 154, 1449–1457.

    Article  Google Scholar 

  17. Wolf, P. A., Abbott, R. D., & Kannel, W. B. (1991). Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke, 22, 983–988.

    PubMed  CAS  Google Scholar 

  18. Fang, M. C., Singer, D. E., Chang, Y., et al. (2005). Gender differences in the risk of ischemic stroke and peripheral embolism in atrial fibrillation: the AnTicoagulation and risk factors in atrial fibrillation (ATRIA) study. Circulation, 112, 1687–1691.

    Article  PubMed  Google Scholar 

  19. Gage, B. F., Waterman, A. D., Shannon, W., Boechler, M., Rich, M. W., & Radford, M. J. (2001). Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. Journal of the American Medical Association, 285, 2864–2870.

    Article  PubMed  CAS  Google Scholar 

  20. Franchini, M. (2006). Hemostasis and aging. Critical Reviews in Oncology/Hematology, 60(2), 144–151.

    Article  PubMed  Google Scholar 

  21. Wilkerson, W. R., & Sane, D. C. (2002). Aging and thrombosis. Seminars in Thrombosis and Hemostasis, 28, 555–568.

    Article  PubMed  CAS  Google Scholar 

  22. Benjamin, E. J., Wolf, P. A., D’Agostino, R. B., Silbershatz, H., Kannal, W. B., & Levy, D. (1998). Impact of atrial fibrillation on the risk of death: the Framingham Heart Study. Circulation, 98, 946–952.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michael W. Rich.

Additional information

This work was supported by a grant from the National Institute on Aging (R13 AG23743, Michael W. Rich, MD, PI)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rich, M.W. Epidemiology of atrial fibrillation. J Interv Card Electrophysiol 25, 3–8 (2009). https://doi.org/10.1007/s10840-008-9337-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10840-008-9337-8

Keywords

Navigation