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Surgery for ventricular tachycardia in patients undergoing surgical ventricular restoration: The Karolinska approach

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Abstract

This article presents a review on the efficacy of surgical ventricular restoration and direct surgery for ventricular tachycardia in patients with left ventricular aneurysm or dilated ischemic cardiomyopathy. The procedure includes a non-electrophysiologically guided subtotal endocardiectomy and cryoablation in addition to endoventricular patch plasty of the left ventricle. Coronary artery bypass surgery and mitral valve repair are performed concomitantly as needed. In our experience, this procedure yielded a 90% success rate in terms of freedom from spontaneous ventricular tachycardia, with an early mortality rate of 3.8%. A practical guide to the pre- and postoperative management of these patients is provided.

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References

  1. Swedberg, K., Writing, C., Cleland, J., Dargie, H., Drexler, H., Follath, F., et al. (2005). Guidelines for the diagnosis and treatment of chronic heart failure: Executive summary (update 2005): The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. European Heart Journal, 26, 1115–1140.

    Article  PubMed  CAS  Google Scholar 

  2. Jessup, M., & Brozena, S. (2003). Heart failure. New England Journal of Medicine, 348, 2007–2018.

    Article  PubMed  Google Scholar 

  3. Pfeffer, M. A., Braunwald, E., Moye, L. A., Basta, L., Brown, E. J., Jr., Cuddy, T. E., et al. (1992). Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. New England Journal of Medicine, 327, 669–677.

    Article  PubMed  CAS  Google Scholar 

  4. Gaudron, P., Eilles, C., Kugler, I., & Ertl, G. (1993). Progressive left ventricular dysfunction and remodeling after myocardial infarction. Potential mechanisms and early predictors. Circulation, 87, 755–763.

    PubMed  CAS  Google Scholar 

  5. White, H. D., Norris, R. M., Brown, M. A., Brandt, P. W., Whitlock, R. M., & Wild, C. J. (1987). Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation, 76, 44–51.

    PubMed  CAS  Google Scholar 

  6. Dor, V. (2004). Surgical remodeling of left ventricle. The Surgical Clinics of North America, 84, 27–43.

    Article  PubMed  Google Scholar 

  7. Menicanti, L., & Di Donato, M. (2002). The Dor procedure: What has changed after fifteen years of clinical practice? Journal of Thoracic and Cardiovascular Surgery, 124, 886–890.

    Article  PubMed  Google Scholar 

  8. Mickleborough, L. L., Merchant, N., Ivanov, J., Rao, V., & Carson, S. (2004). Left ventricular reconstruction: Early and late results. Journal of Thoracic and Cardiovascular Surgery, 128, 27–37.

    Article  PubMed  Google Scholar 

  9. Caldeira, C., & McCarthy, P. M. (2001). A simple method of left ventricular reconstruction without patch for ischemic cardiomyopathy. Annals of Thoracic Surgery, 72, 2148–2149.

    Article  PubMed  CAS  Google Scholar 

  10. Wilber, D. J., Olshansky, B., Moran, J. F., & Scanlon, P. J. (1990). Electrophysiological testing and nonsustained ventricular tachycardia. Use and limitations in patients with coronary artery disease and impaired ventricular function. Circulation, 82, 350–358.

    PubMed  CAS  Google Scholar 

  11. Bourke, J. P., Richards, D. A., Ross, D. L., Wallace, E. M., McGuire, M. A., & Uther, J. B. (1991). Routine programmed electrical stimulation in survivors of acute myocardial infarction for prediction of spontaneous ventricular tachyarrhythmias during follow-up: Results, optimal stimulation protocol and cost-effective screening. Journal of the American College of Cardiology, 18, 780–788.

    Article  PubMed  CAS  Google Scholar 

  12. Cox, J. L. (2004). Cardiac surgery for arrhythmias. Journal of Cardiovascular Electrophysiology, 15, 250–262.

    Article  PubMed  Google Scholar 

  13. Josephson, M. E. (1993). Clinical cardiac electrophysiology, techniques and interpretations (2nd ed.). Philadelphia: Lea & Febiger.

    Google Scholar 

  14. Buxton, A. E., Lee, K. L., DiCarlo, L., Gold, M. R., Greer, G. S., Prystowsky, E. N., et al. (2000). Electrophysiologic testing to identify patients with coronary artery disease who are at risk for sudden death. New England Journal of Medicine, 342, 1937–1945.

    Article  PubMed  CAS  Google Scholar 

  15. Brugada, J., Aguinaga, L., Mont, L., Betriu, A., Mulet, J., & Sanz, G. (2001). Coronary artery revascularization in patients with sustained ventricular arrhythmias in the chronic phase of a myocardial infarction: Effects on the electrophysiologic substrate and outcome. Journal of the American College of Cardiology, 37, 529–533.

    Article  PubMed  CAS  Google Scholar 

  16. Kaul, T. K., Fields, B. L., Riggins, L. S., Wyatt, D. A., & Jones, C. R. (1998). Ventricular arrhythmia following successful myocardial revascularization: Incidence, predictors and prevention. European Journal of Cardio-Thoracic Surgery, 13, 629–636.

    Article  PubMed  CAS  Google Scholar 

  17. O’Rourke, R. A. (1992). Role of myocardial revascularization in sudden cardiac death. Circulation, 85, I112–I117.

    PubMed  CAS  Google Scholar 

  18. Couch, O. A., Jr. (1959). Cardiac aneurysm with ventricular tachycardia and subsequent excision of aneurysm; case report. Circulation, 20, 251–253.

    PubMed  Google Scholar 

  19. Guiraudon, G., Fontaine, G., Frank, R., Escande, G., Etievent, P., & Cabrol, C. (1978). Encircling endocardial ventriculotomy: A new surgical treatment for life-threatening ventricular tachycardias resistant to medical treatment following myocardial infarction. Annals of Thoracic Surgery, 26, 438–444.

    Article  PubMed  CAS  Google Scholar 

  20. Josephson, M. E., Harken, A. H., & Horowitz, L. N. (1979). Endocardial excision: A new surgical technique for the treatment of recurrent ventricular tachycardia. Circulation, 60, 1430–1439.

    PubMed  CAS  Google Scholar 

  21. Cox, J. L., Gallagher, J. J., & Ungerleider, R. M. (1982). Encircling endocardial ventriculotomy for refractory ischemic ventricular tachycardia. IV. Clinical indication, surgical technique, mechanism of action, and results. Journal of Thoracic and Cardiovascular Surgery, 83, 865–872.

    PubMed  CAS  Google Scholar 

  22. Moran, J. M., Kehoe, R. F., Loeb, J. M., Lichtenthal, P. R., Sanders, J. H., Jr., & Michaelis, L. L. (1982). Extended endocardial resection for the treatment of ventricular tachycardia and ventricular fibrillation. Annals of Thoracic Surgery, 34, 538–552.

    Article  PubMed  CAS  Google Scholar 

  23. Ostermeyer, J., Borggrefe, M., Breithardt, G., Podczek, A., Goldmann, A., Schoenen, J. D., et al. (1987). Direct operations for the management of life-threatening ischemic ventricular tachycardia. Journal of Thoracic and Cardiovascular Surgery, 94, 848–865.

    PubMed  CAS  Google Scholar 

  24. Bakker, P. F., de Lange, F., Hauer, R. N., Derksen R., & de Bakker, J. M. (2001). Sequential map-guided endocardial resection for ventricular tachycardia improves outcome. European Journal of Cardio-Thoracic Surgery, 19, 448–453.

    Article  PubMed  CAS  Google Scholar 

  25. Krafchek, J., Lawrie, G. M., Roberts, R., Magro, S. A., & Wyndham, C. R. (1986). Surgical ablation of ventricular tachycardia: Improved results with a map-directed regional approach. Circulation, 73, 1239–1247.

    PubMed  CAS  Google Scholar 

  26. Rastegar, H., Link, M. S., Foote, C. B., Wang, P. J., Manolis, A. S., & Estes, N. A., 3rd. (1996). Perioperative and long-term results with mapping-guided subendocardial resection and left ventricular endoaneurysmorrhaphy. Circulation, 94, 1041–1048.

    PubMed  CAS  Google Scholar 

  27. Pirk, J., Bytesnik, J., Kautzner, J., Peichl, P., Vancura, V., Lefflerova, K., et al. (2004). Surgical ablation of post-infarction ventricular tachycardia guided by mapping in sinus rhythm: Long term results. European Journal of Cardio-Thoracic Surgery, 26, 323–329.

    Article  PubMed  Google Scholar 

  28. Harken, A. H., Horowitz, L. N., & Josephson, M. E. (1980). Comparison of standard aneurysmectomy and aneurysmectomy with directed endocardial resection for the treatment of recurrent sustained ventricular tachycardia. Journal of Thoracic and Cardiovascular Surgery, 80, 527–534.

    PubMed  CAS  Google Scholar 

  29. Wellens, F., Geelen, P., Demirsoy, E., Van Praet, F., De Geest, R., Degrieck, I., et al. (2002). Surgical treatment of tachyarrhythmias due to postinfarction left ventricular aneurysm with endoaneurysmorrhaphy and cryoablation. European Journal of Cardio-Thoracic Surgery, 22, 771–776.

    Article  PubMed  Google Scholar 

  30. Frapier, J. M., Hubaut, J. J., Pasquie, J. L., & Chaptal, P. A. (1998). Large encircling cryoablation without mapping for ventricular tachycardia after anterior myocardial infarction: Long-term outcome. Journal of Thoracic and Cardiovascular Surgery, 116, 578–583.

    Article  PubMed  CAS  Google Scholar 

  31. Thakur, R. K., Guiraudon, G. M., Klein, G. J., Yee, R., & Guiraudon, C. M. (1994). Intraoperative mapping is not necessary for VT surgery. Pacing and Clinical Electrophysiology, 17, 2156–2162.

    Article  PubMed  CAS  Google Scholar 

  32. Nath, S., Haines, D. E., Kron, I. L., & DiMarco, J. P. (1994). The long-term outcome of visually directed subendocardial resection in patients without inducible or mappable ventricular tachycardia at the time of surgery. Journal of Cardiovascular Electrophysiology, 5, 399–407.

    Article  PubMed  CAS  Google Scholar 

  33. Dor, V., Sabatier, M., Montiglio, F., Rossi, P., Toso, A., & Di Donato, M. (1994). Results of nonguided subtotal endocardiectomy associated with left ventricular reconstruction in patients with ischemic ventricular arrhythmias. Journal of Thoracic and Cardiovascular Surgery, 107, 1301–1307.

    PubMed  CAS  Google Scholar 

  34. Demaria, R. G., Mukaddirov, M., Rouviere, P., Barbotte, E., Celton, B., Albat, B., et al. (2005). Long-term outcomes after cryoablation for ventricular tachycardia during surgical treatment of anterior ventricular aneurysms. Pacing and Clinical Electrophysiology, 28(Suppl 1), 168–171.

    Article  Google Scholar 

  35. Mickleborough, L. L., Mizuno, S., Downar, E., & Gray, G. C. (1992). Late results of operation for ventricular tachycardia. Annals of Thoracic Surgery, 54, 832–838.

    Article  PubMed  CAS  Google Scholar 

  36. Sartipy, U., Albåge, A., Strååt, E., Insulander, P., & Lindblom, D. (2006). Surgery for ventricular tachycardia in patients undergoing left ventricular reconstruction by the Dor procedure. Annals of Thoracic Surgery, 81, 65–71.

    Article  PubMed  Google Scholar 

  37. Menicanti, L., & Di Donato, M. (2005). Left ventricular aneurysm/reshaping techniques. Multimedia Manual of Cardiothoracic Surgery. DOI 10.1510/mmcts.2004.000596.

  38. Cox, J. L. (1989). Patient selection criteria and results of surgery for refractory ischemic ventricular tachycardia. Circulation, 79, 163–177.

    Google Scholar 

  39. Koilpillai, C., Quinones, M. A., Greenberg, B., Limacher, M. C., Shindler, D., Pratt, C. M., et al. (1996). Relation of ventricular size and function to heart failure status and ventricular dysrhythmia in patients with severe left ventricular dysfunction. American Journal of Cardiology, 77, 606–611.

    Article  PubMed  CAS  Google Scholar 

  40. Di Donato, M., Toso, A., Dor, V., Sabatier, M., Barletta, G., Menicanti, L., et al. (2004). Surgical ventricular restoration improves mechanical intraventricular dyssynchrony in ischemic cardiomyopathy. Circulation, 109, 2536–2543.

    Article  PubMed  Google Scholar 

  41. Zagrodzky, J. D., Ramaswamy, K., Page, R. L., Joglar, J. A., Sheehan, C. J., Smith, M. L., et al. (2001). Biventricular pacing decreases the inducibility of ventricular tachycardia in patients with ischemic cardiomyopathy. American Journal of Cardiology, 87, 1208–1210.

    Article  PubMed  CAS  Google Scholar 

  42. Higgins, S. L., Yong, P., Sheck, D., McDaniel, M., Bollinger, F., Vadecha, M., et al. (2000). Biventricular pacing diminishes the need for implantable cardioverter defibrillator therapy. Ventak CHF Investigators. Journal of the American College of Cardiology, 36, 824–827.

    Article  PubMed  CAS  Google Scholar 

  43. Kies, P., Bax, J. J., Molhoek, S. G., Bleeker, G. B., Zeppenfeld, K., Bootsma, M., et al. (2004). Effect of left ventricular remodeling after cardiac resynchronization therapy on frequency of ventricular arrhythmias. American Journal of Cardiology, 94, 130–132.

    Article  PubMed  Google Scholar 

  44. Walker, S., Levy, T. M., Rex, S., Brant, S., Allen, J., Ilsley, C. J. D., et al. (2000). Usefulness of suppression of ventricular arrhythmia by biventricular pacing in severe congestive cardiac failure. American Journal of Cardiology, 86, 231–233.

    Article  PubMed  CAS  Google Scholar 

  45. Breithardt, O. A., Stellbrink, C., Herbots, L., Claus, P., Sinha, A. M., Bijnens, B., et al. (2003). Cardiac resynchronization therapy can reverse abnormal myocardial strain distribution in patients with heart failure and left bundle branch block. Journal of the American College of Cardiology, 42, 486–494.

    Article  PubMed  Google Scholar 

  46. Matthias Bechtel, J. F., Tolg, R., Graf, B., Richardt, G., Noetzold, A., Kraatz, E. G., et al. (2004). High incidence of sudden death late after anterior LV-aneurysm repair. European Journal of Cardio-Thoracic Surgery, 25, 807–811.

    Article  PubMed  CAS  Google Scholar 

  47. O’Neill, J. O., Starling, R. C., Khaykin, Y., McCarthy, P. M., Young, J. B., Hail, M., et al. (2005). Residual high incidence of ventricular arrhythmias after left ventricular reconstructive surgery. Journal of Thoracic and Cardiovascular Surgery, 130, 1250–1256.

    Article  PubMed  Google Scholar 

  48. Mickleborough, L. L., Usui, A., Downar, E., Harris, L., Parson, I., & Gray, G. (1990). Transatrial balloon technique for activation mapping during operations for recurrent ventricular tachycardia. Journal of Thoracic and Cardiovascular Surgery, 99, 227–232.

    PubMed  CAS  Google Scholar 

  49. Bardy, G. H., Lee, K. L., Mark, D. B., Poole, J. E., Packer, D. L., Boineau, R., et al. (2005). Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. New England Journal of Medicine, 352, 225–237.

    Article  PubMed  CAS  Google Scholar 

  50. Moss, A. J., Zareba, W., Hall, W. J., Klein, H., Wilber, D. J., Cannom, D. S., et al. (2002). Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. New England Journal of Medicine, 346, 877–883.

    Article  PubMed  Google Scholar 

  51. Steinberg, J. S., Fischer, A. V. I., Wang, P., Schuger, C., Daubert, J., McNitt, S., et al. (2005). The clinical implications of cumulative right ventricular pacing in the Multicenter Automatic Defibrillator Trial II. Journal of Cardiovascular Electrophysiology, 16, 359–365.

    Article  PubMed  Google Scholar 

  52. Bigger, J. T., & The Coronary Artery Bypass Graft Patch Trial I. (1997). Prophylactic use of implanted cardiac defibrillators in patients at high risk for ventricular arrhythmias after coronary artery bypass graft surgery. New England Journal of Medicine, 337, 1569–1575.

    Article  PubMed  Google Scholar 

  53. Goldenberg, I., Moss, A. J., McNitt, S., Zareba, W., Hall, W. J., Andrews, M. L., et al. (2006). Time dependence of defibrillator benefit after coronary revascularization in the Multicenter Automatic Defibrillator Implantation Trial (MADIT)-II. Journal of the American College of Cardiology, 47, 1811–1817.

    Article  PubMed  Google Scholar 

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Correspondence to Ulrik Sartipy.

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Sartipy, U., Albåge, A., Insulander, P. et al. Surgery for ventricular tachycardia in patients undergoing surgical ventricular restoration: The Karolinska approach. J Interv Card Electrophysiol 19, 171–178 (2007). https://doi.org/10.1007/s10840-007-9152-7

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