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Table 2 Summary of results in terms of success percentages at an RMSD threshold of 2.0 Å  for the top pose family, top 2, 5, and 10

From: Knowledge-guided docking: accurate prospective prediction of bound configurations of novel ligands using Surflex-Dock

Target N test Top family Top 2 Top 5 Top 10
PTP1b 52 50 67 77 83
BACE1 103 57 71 85 88
MAPK14 92 71 79 89 93
HIV-PR 127 55 69 75 80
Thrombin 114 68 76 81 83
\(\hbox {PPAR}\gamma \) 62 31 34 39 45
CA-II 128 63 77 88 94
\(\hbox {HSP90}\alpha \) 57 57 72 91 91
CDK2 127 75 85 93 96
HIV-RT 46 63 78 87 91
Overall 949 62 74 83 87