References
Li R, Zhu J. Effects of aneuploidy on cell behaviour and function. Nat Rev Mol Cell Biol. 2022;4:250–65. https://doi.org/10.1038/s41580-021-00436.
Thomas C, Cavazza T, Schuh M. Aneuploidy in human eggs: contributions of the meiotic spindle. Biochem Soc Trans. 2021;49(1):107–18.
Currie CE, Ford E, Benham Whyte L, Taylor DM, Mihalas BP, Erent M, et al. The first mitotic division of human embryos is highly error prone. Nat Commun. 2022;13(1):6755.
Palmerola KL, Amrane S, De Los Angeles A, Xu S, Wang N, de Pinho J, et al. Replication stress impairs chromosome segregation and preimplantation development in human embryos. Cell. 2022;185(16):2988-3007 e20.
Kort DH, Chia G, Treff NR, Tanaka AJ, Xing T, Vensand LB, et al. Human embryos commonly form abnormal nuclei during development: a mechanism of DNA damage, embryonic aneuploidy, and developmental arrest. Hum Reprod. 2016;31(2):312–23.
Daughtry BL, Rosenkrantz JL, Lazar N, Redmayne N, Nevonen KA, Carbone L, et al. Aneuploidy tolerance in rhesus macaque pre-implantation embryos via micronuclei formation, cellular fragmentation, and blastomere exclusion. Reprod Fertil Dev. 2016;29(1):110–1.
Daughtry BL, Rosenkrantz JL, Lazar NH, Fei SS, Redmayne N, Torkenczy KA, et al. Single-cell sequencing of primate preimplantation embryos reveals chromosome elimination via cellular fragmentation and blastomere exclusion. Genome Res. 2019;29(3):367–82.
Ottolini CS, Kitchen J, Xanthopoulou L, Gordon T, Summers MC, Handyside AH. Tripolar mitosis and partitioning of the genome arrests human preimplantation development in vitro. Sci Rep. 2017;7(1):9744.
McCoy RC, Newnham LJ, Ottolini CS, Hoffmann ER, Chatzimeletiou K, Cornejo OE, et al. Tripolar chromosome segregation drives the association between maternal genotype at variants spanning PLK4 and aneuploidy in human preimplantation embryos. Hum Mol Genet. 2018;27(14):2573–85.
Neitzel H, Varon R, Chughtai S, Dartsch J, Dutrannoy-Tonsing V, Nurnberg P, et al. Transmission ratio distortion of mutations in the master regulator of centriole biogenesis PLK4. Hum Genet. 2022;141(11):1785–94.
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher's note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Albertini, D.F. The fan base for embryo selection strategies: enlightened or flummoxed. J Assist Reprod Genet 39, 2437–2438 (2022). https://doi.org/10.1007/s10815-022-02672-0
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10815-022-02672-0