Skip to main content
Log in

Insights into the utility of preimplantation genetic testing from data collected by the HFEA

  • Commentary
  • Published:
Journal of Assisted Reproduction and Genetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Availability of data and material

Supplementary file provided.

Code availability

Not applicable.

References

  1. Sanders KD, Silvestri G, Gordon T, Griffin DK. Analysis of IVF live birth outcomes with and without preimplantation genetic testing for aneuploidy (PGT-A): UK Human Fertilisation and Embryology Authority data collection 2016–2018. J Assist Reprod Genet. 2021. https://doi.org/10.1007/s10815-021-02349-0.

    Article  PubMed  Google Scholar 

  2. Renwick P, Trussler J, Lashwood A, Braude P, Ogilvie CM. Preimplantation genetic haplotyping: 127 diagnostic cycles demonstrating a robust, efficient alternative to direct mutation testing on single cells. Reprod Biomed Online. 2010;20:470–6. https://doi.org/10.1016/j.rbmo.2010.01.006.

    Article  PubMed  Google Scholar 

  3. Ben-Nagi J, Jones B, Naja R, Amer A, Sunkara S, SenGupta S, Serhal P. Live birth rate is associated with oocyte yield and number of biopsied and suitable blastocysts to transfer in preimplantation genetic testing (PGT) cycles for monogenic disorders and chromosomal structural rearrangements. Eur J Obstet Gynecol Reprod Biol X. 2019;4:100055. https://doi.org/10.1016/j.eurox.2019.100055.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Pagliardini L, Viganò P, Alteri A, Corti L, Somigliana E, Papaleo E. Shooting STAR: reinterpreting the data from the ‘Single Embryo TrAnsfeR of Euploid Embryo’ randomized clinical trial. Reprod Biomed Online. 2020;40:475–8. https://doi.org/10.1016/j.rbmo.2020.01.015.

    Article  CAS  PubMed  Google Scholar 

  5. Scriven PN. A tale of two studies: now is no longer the best of times for preimplantation genetic testing for aneuploidy (PGT-A). J Assist Reprod Genet. 2020;37:673–6. https://doi.org/10.1007/s10815-020-01712-x.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Scriven PN. PGT-SR (reciprocal translocation) using trophectoderm sampling and next-generation sequencing: insights from a virtual trial. J Assist Reprod Genet. 2021;38:1971–8. https://doi.org/10.1007/s10815-021-02174-5.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

The author is responsible for the content and writing of the article.

Corresponding author

Correspondence to Paul N. Scriven.

Ethics declarations

Ethics approval

Not applicable.

Consent to participate

Not applicable.

Consent for publication

Not applicable.

Conflict of interest

The author declares no competing interests.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (XLSX 527 KB)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Scriven, P.N. Insights into the utility of preimplantation genetic testing from data collected by the HFEA. J Assist Reprod Genet 38, 3065–3068 (2021). https://doi.org/10.1007/s10815-021-02369-w

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10815-021-02369-w

Navigation