Successful embryo cryopreservation immediately following a full-term delivery in a woman with newly diagnosed Ewing’s sarcoma
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Ewing’s sarcoma is an aggressive, small blue round cell malignancy, affecting one per million people in the USA . Albeit extremely rare, the incidence is much higher in children and young adults, a population who often have not completed their child-bearing. In fact, it accounts for approximately 10% of malignant bone cancers in children and young adults, and 3% of all childhood malignancies . Unfortunately, 25% of patients who present with a clinically apparent localized tumor may also already have signs of occult metastatic disease . Most commonly, metastases are found in the lungs, bones, and bone marrow .
While surgery remains a fundamental treatment strategy, the introduction of new chemotherapy agents and the combination of chemo and local radiotherapy (conformational RT and intensity-modulated RT) have led to increased 5-year survival rates from less than 15% to 65–70% for patients with localized disease and to 25–30% for those with metastatic disease [1...
Compliance with ethical standards
Informed consent was obtained from the patient described in this case report.
Conflict of interest
The authors declare that they have no conflict of interest.
- 6.Combination chemotherapy with or without ganitumab in treating patients with newly diagnosed metastatic Ewing sarcoma. (2018). Retrieved from http://clinicaltrials.gov/ct2 (Identification No. NCT02306161).