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Split happens: a case of consecutive monozygotic twin pregnancies following elective single-embryo transfer in a 40-year old woman using donor oocytes

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References

  1. Mercan R, Oktem O, Salar Z, Nuhoglu A, Balaban B, Urman B. Conjoined twins after intracytoplasmic sperm injection and transfer of day-3 embryos. Fertil Steril. 2011;96:e111–4.

    Article  PubMed  Google Scholar 

  2. Sobek A, Prochazka M, Klaskova E, Lubusky M, Pilka R. High incidence of monozygotic twinning in infertility treatment. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 2016;160:358–62.

  3. Aston KI, Peterson CM, Carrell DT. Monozygotic twinning associated with assisted reproductive technologies: a review. Reproduction (Cambridge, England). 2008;136:377–86.

    Article  CAS  Google Scholar 

  4. Song B, Wei ZL, Xu XF, Wang X, He XJ, Wu H, et al. Prevalence and risk factors of monochorionic diamniotic twinning after assisted reproduction: a six-year experience base on a large cohort of pregnancies. PLoS One. 2017;12:e0186813.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Vela G, Luna M, Barritt J, Sandler B, Copperman AB. Monozygotic pregnancies conceived by in vitro fertilization: understanding their prognosis. Fertil Steril. 2011;95:606–10.

    Article  PubMed  Google Scholar 

  6. Kawachiya S, Bodri D, Shimada N, Kato K, Takehara Y, Kato O. Blastocyst culture is associated with an elevated incidence of monozygotic twinning after single embryo transfer. Fertil Steril. 2011;95:2140–2.

    Article  PubMed  Google Scholar 

  7. Knopman J, Krey LC, Lee J, Fino ME, Novetsky AP, Noyes N. Monozygotic twinning: an eight-year experience at a large IVF center. Fertil Steril. 2010;94:502–10.

    Article  PubMed  Google Scholar 

  8. Chang HJ, Lee JR, Jee BC, Suh CS, Kim SH. Impact of blastocyst transfer on offspring sex ratio and the monozygotic twinning rate: a systematic review and meta-analysis. Fertil Steril. 2009;91:2381–90.

    Article  PubMed  Google Scholar 

  9. Milki AA, Jun SH, Hinckley MD, Behr B, Giudice LC, Westphal LM. Incidence of monozygotic twinning with blastocyst transfer compared to cleavage-stage transfer. Fertil Steril. 2003;79:503–6.

    Article  PubMed  Google Scholar 

  10. Blickstein I, Keith LG. On the possible cause of monozygotic twinning: lessons from the 9-banded armadillo and from assisted reproduction. Twin Res Hum Genet. 2007;10:394–9.

    Article  PubMed  Google Scholar 

  11. Moayeri SE, Behr B, Lathi RB, Westphal LM, Milki AA. Risk of monozygotic twinning with blastocyst transfer decreases over time: an 8-year experience. Fertil Steril. 2007;87:1028–32.

    Article  PubMed  Google Scholar 

  12. Steinman G. Mechanisms of twinning. IV Sex preference and lactation. J Reprod Med. 2001;46:1003–7.

    PubMed  CAS  Google Scholar 

  13. Menezo YJ, Sakkas D. Monozygotic twinning: is it related to apoptosis in the embryo? Hum Reprod (Oxford, England). 2002;17:247–8.

    Article  Google Scholar 

  14. Franasiak JM, Dondik Y, Molinaro TA, Hong KH, Forman EJ, Werner MD, et al. Blastocyst transfer is not associated with increased rates of monozygotic twins when controlling for embryo cohort quality. Fertil Steril. 2015;103:95–100.

    Article  PubMed  Google Scholar 

  15. Farah N, Hogan J, Johnson S, Stuart B, Daly S. Prospective risk of fetal death in uncomplicated monochorionic twins. Acta Obstet Gynecol Scand. 2012;91:382–5.

    Article  PubMed  Google Scholar 

  16. Jauniaux E, Ben-Ami I, Maymon R. Do assisted-reproduction twin pregnancies require additional antenatal care? Reprod BioMed Online. 2013;26:107–19.

    Article  PubMed  CAS  Google Scholar 

  17. Gee RE, Dickey RP, Xiong X, Clark LS, Pridjian G. Impact of monozygotic twinning on multiple births resulting from in vitro fertilization in the United States, 2006-2010. Am J Obstet Gynecol. 2014;210:468.e1–6.

    Article  Google Scholar 

  18. Kalra SK, Molinaro TA. The association of in vitro fertilization and perinatal morbidity. Semin Reprod Med. 2008;26:423–35.

    Article  PubMed  Google Scholar 

  19. Elective single-embryo transfer. Fertil Steril. 2012;97:835–42.

    Article  Google Scholar 

  20. Multiple gestation associated with infertility therapy: an American Society for Reproductive Medicine Practice Committee opinion. Fertil Steril 2012;97:825–34.

  21. Blastocyst culture and transfer in clinical-assisted reproduction: a committee opinion. Fertil Steril 2013;99:667–72.

  22. Criteria for number of embryos to transfer: a committee opinion. Fertil Steril 2013;99:44–6.

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Correspondence to Alexis-Danielle Roberts.

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Roberts, AD., Schmidt, R. & Shah, M. Split happens: a case of consecutive monozygotic twin pregnancies following elective single-embryo transfer in a 40-year old woman using donor oocytes. J Assist Reprod Genet 35, 1529–1532 (2018). https://doi.org/10.1007/s10815-018-1218-1

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  • DOI: https://doi.org/10.1007/s10815-018-1218-1

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