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The influence of body mass index on pregnancy outcome following single-embryo transfer

  • Assisted Reproduction Technologies
  • Published:
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Abstract

Purpose

The association between obesity and reproductive outcome is controversial. The aim of this study is to evaluate the effects of obesity on clinical pregnancy rates following transfer of a single fresh embryo.

Methods

A retrospective cohort study was conducted at a single tertiary medical center, including all first, fresh, single-embryo transfers using non-donor oocytes, during 2008–2013. We compared clinical pregnancy rate and pregnancy outcomes of singleton live births resulting from the transfer of a single fresh embryo in normal weight, overweight, and obese women, defined as body mass index (BMI) < 25 kg/m2, ≥ 25 BMI <30 kg/m2, and BMI ≥ 30 kg/m2, respectively.

Results

Overall, 1345 cases met the inclusion criteria with 864 single-embryo transfers (SETs) in normal weight women, 292 in overweight women, and 189 SETs in obese women, resulting in 538 clinical pregnancies and 354 singleton births. The clinical pregnancy rate per transfer was similar among the three groups (41.3, 37.6, 37.5%, respectively, p = 0.416). Similarly, there were no significant differences in live births or ongoing pregnancies. On multivariate logistic regression analysis, BMI did not impact the likelihood for clinical pregnancy (OR 0.98, 95% CI 0.96–1.008, p = 0.216).

Conclusions

Our study demonstrated that obesity has no detrimental effect on the clinical pregnancy rate resulting from the transfer of a single fresh embryo.

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Author information

Author notes

  1. Avi Ben-Haroush and Ido Sirota contributed equally to this work.

Authors and Affiliations

  1. Helen Schneider Hospital for Women, Rabin Medical Center, Petah Tikva, Israel

    Avi Ben-Haroush, Ido Sirota, Lina Salman & Galia Oron

  2. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

    Avi Ben-Haroush, Lina Salman & Galia Oron

  3. Department of Obstetrics and Gynecology, New York-Presbyterian/Queens, Flushing, NY, USA

    Ido Sirota

  4. Weill Cornell Medicine, New York, NY, USA

    Ido Sirota

  5. Department of Obstetrics and Gynecology, McGill University, Montreal, QC, Canada

    Weon-Young Son, Togas Tulandi, Hananel Holzer & Galia Oron

  6. IVF Unit, Division of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel

    Hananel Holzer

  7. School of Medicine, Hebrew University, Jerusalem, Israel

    Hananel Holzer

Authors
  1. Avi Ben-Haroush
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  2. Ido Sirota
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  3. Lina Salman
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  4. Weon-Young Son
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  5. Togas Tulandi
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  6. Hananel Holzer
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  7. Galia Oron
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Corresponding author

Correspondence to Galia Oron.

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The authors declare that they have no conflict of interest.

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Ben-Haroush, A., Sirota, I., Salman, L. et al. The influence of body mass index on pregnancy outcome following single-embryo transfer. J Assist Reprod Genet 35, 1295–1300 (2018). https://doi.org/10.1007/s10815-018-1186-5

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  • DOI: https://doi.org/10.1007/s10815-018-1186-5

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