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Empty follicle syndrome after GnRHa triggering versus hCG triggering in COS

Journal of Assisted Reproduction and Genetics volume 29, pages 249–253 (2012)Cite this article

Abstract

Purpose

This study aimed to explore the incidence of empty follicle syndrome (EFS) in oocyte donors who had final oocyte maturation triggered with GnRHa and to compare the incidence of EFS in this group of patients with IVF patients who had final oocyte maturation with hCG.

Methods

Data including 2034 oocyte donation cycles and 1433 IVF cycles performed between years 2009 and 2010 was retrospectively analyzed to identify cases of EFS in each group.

Results

The incidence of EFS in the two groups did not differ significantly, 3.5% versus 3.1%, (n.s.).

Conclusions

This large retrospective analysis indicates that the incidence of EFS is not increased after GnRHa triggering as compared to hCG triggering.

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Acknowledgements

The authors would like to acknowledge Dr Claudio Bonomini for his invaluable help in data search.

The authors disclose any potential conflict of interest.

Author information

Affiliations

  1. FIV Valencia, Santa Rosa 12, 46021, Valencia, Spain

    Juan C. Castillo

  2. IVI Madrid, Madrid, Spain

    Juan Garcia-Velasco

  3. The Fertility Clinic, Department D, Odense University Hospital, Odense, Denmark

    Peter Humaidan

Authors
  1. Juan C. Castillo
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  2. Juan Garcia-Velasco
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  3. Peter Humaidan
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Corresponding author

Correspondence to Juan C. Castillo.

Additional information

Capsule

Empty follicle syndrome is a condition in which no oocytes are retrieved after ovarian stimulation for IVF. The incidence seems to be similar after GnRHa triggering in oocyte donors as compared to hCG triggering in IVF patients.

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Castillo, J.C., Garcia-Velasco, J. & Humaidan, P. Empty follicle syndrome after GnRHa triggering versus hCG triggering in COS. J Assist Reprod Genet 29, 249–253 (2012). https://doi.org/10.1007/s10815-011-9704-8

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  • DOI: https://doi.org/10.1007/s10815-011-9704-8

Keywords

  • GnRH agonist
  • GnRH antagonist
  • GnRHa triggering
  • hCG
  • Empty follicle syndrome