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Monozygotic bichorionic twinning after transfer of a single frozen/thawed embryo that has undergone quarter laser-assisted zona thinning: A case report

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Abstract

Purpose: To present the occurrence of a monozygotic bichorionic twinning after the transfer of a single frozen/thawed embryo has undergone assisted zona hatching (AZH), using a non contact laser.

Methods: A 33-year-old woman who underwent single frozen embryo replacement (FER). Before transfer, the patient was treated with GnRH agonist and with substitutive therapy (estrogens and progesterone).

Conclusions: We are absolutely certain that we are reporting a monozygotic bichorionic pregnancy: a single frozen/thawed embryo was transferred and no concomitant spontaneous conception was possible. Moreover, molecular biology assessment for polymorphisms confirmed clinical findings. The possibility of the occurrence of a monozygotic bichorionic twinning after the transfer of a single frozen/thawed embryo should be borne in mind and its incidence will have to be studied further.

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Authors and Affiliations

  1. ANDROS Day Surgery, Reproductive Medicine Unit, Via Ausonia 43/45, Palermo, I-90144, Italy

    A. Allegra, F. Sammartano, P. Scaglione, F. Coffaro, A. Marino & A. Volpes

Authors
  1. A. Allegra
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  2. F. Sammartano
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  3. P. Scaglione
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  4. F. Coffaro
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  5. A. Marino
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  6. A. Volpes
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Corresponding author

Correspondence to A. Volpes.

Additional information

The abstract of this case report was presented, as poster presentation, at the 13th World Congress on In Vitro Fertilization, Assisted Reproduction and Genetics, Istanbul, Turkey, May 26–29, 2005.

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Allegra, A., Sammartano, F., Scaglione, P. et al. Monozygotic bichorionic twinning after transfer of a single frozen/thawed embryo that has undergone quarter laser-assisted zona thinning: A case report. J Assist Reprod Genet 22, 437–441 (2005). https://doi.org/10.1007/s10815-005-7483-9

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  • DOI: https://doi.org/10.1007/s10815-005-7483-9

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