The efficiencies of several multivariate methods of recognition of drug classes in primary packaging using THz transmission spectra are compared. The advantage of support vector machines is demonstrated with a classification error ≤5.7% for two groups of analgesic drugs with a high level of heterogeneity of samples in the groups.
Similar content being viewed by others
References
W. Su, T. Chao, S. Yang, and Ch. Lin, Seeing through a Black Box: Toward High-Quality Terahertz Tomographic Imaging via Multi-Scale Spatio-Spectral Image Fusion, arxiv.org/abs/2103.16932 (2021).
D. Molter, D. Hubsch, T. Sprenger, K. Hens, K. Nalpantidis, F. Platte, G. Torosyan, R. Beigang, J. Jonuscheit, G. von Freymann, and F. Ellrich, Appl. Sci., 11, No. 3, 950 (2021).
L. Yang, T. Guo, X. Zhang, S. Cao, and X. Ding, Rev. Anal. Chem., 37, No. 3, 20170021 (2018).
Y. Peng, C. Shi, Y. Zhu, M. Gu, and S. Zhuang, PhotoniX, 1, No. 12, 1–18 (2020).
J. Deng, J. Ornik, K. Zhao, E. Ding, M. Koch, and E. Castro-Camus, Opt. Express, 28, No. 21, 30943–30951 (2020).
D. A. Borisevich, A. M. Goncharenko, A. V. Lyakhnovich, G. V. Sinitsyn, and M. A. Khodasevich, J. Appl. Spectrosc., 88, No. 1, 132–136 (2021).
P. F. Taday, Philos. Trans. R. Soc. London A, 362, 351–364 (2004).
G. V. Ayupova, G. M. Latypova, O. I. Urazlina, and A. A. Fedotova, Drug Packaging: Study Guide for Pharmaceutical Technology [in Russian], Izd. Bashgosmeduniversiteta, Ufa (2009), p. 91.
R. Bro and Age K. Smilde, Anal. Methods, 6, 2812–2831 (2014).
K. Vekey, A. Telekes, and A. Vertes (Eds.), Medical Applications of Mass Spectrometry, Elsevier (2008), pp. 141–169.
W. Loh, Int. Stat. Rev., 82, No. 3, 329–348 (2014).
L. A. Berrueta, R. M. Alonso-Salces, and K. Heberger, J. Chromatogr. A, 1158, 196–214 (2007).
Y. Xu, S. Zomer, and R. G. Brereton, Crit. Rev. Anal. Chem., 36, 177–188 (2006).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 88, No. 5, pp. 778–782, September–October, 2021.
Rights and permissions
About this article
Cite this article
Lyakhnovich, A.V., Sinitsyn, G.V., Khodasevich, M.A. et al. Classification of Analgesic Drugs in Primary Packaging by Applying Multivariate Methods to Terahertz Spectra. J Appl Spectrosc 88, 1008–1011 (2021). https://doi.org/10.1007/s10812-021-01272-7
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10812-021-01272-7