We have studied the effect of extracorporeal ultraviolet blood irradiation on cholesterol metabolism in patients with cardiovascular diseases. We have carried out a comprehensive analysis of the spectral characteristics of blood and plasma, gas-exchange and oximetry parameters, and the results of a complete blood count and chemistry panel before and after UV blood irradiation. We have assessed the changes in concentrations of cholesterols (total cholesterol, low-density lipoprotein (LDL) cholesterol, triglycerides) in the blood of the patients in response to a five-day course of UV blood irradiation. The changes in the spectral characteristics of blood and plasma, the chemistry panel, the gas composition, and the fractional hemoglobin composition initiated by absorption of UV radiation are used to discuss the molecular mechanisms for the effect of therapeutic doses of UV radiation on blood cholesterols.
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Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 79, No. 3, pp. 465–470, May–June, 2012.
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Zalesskaya, G.A., Laskina, O.V., Mitkovskaya, N.P. et al. Effect of extracorporeal ultraviolet blood irradiation on blood cholesterol level. J Appl Spectrosc 79, 446–452 (2012). https://doi.org/10.1007/s10812-012-9621-3
- ultraviolet blood irradiation
- absorption spectra of blood and plasma in the UV-visible and IR ranges
- low-density lipoprotein (LDL) cholesterol
- level of hemoglobin oxygen saturation
- active oxygen species