Abstract
We have studied the fluorescent properties of flavonols (quercetin, fisetin, morin, rutin) with the aim of studying possible interaction with hemoglobin and bovine serum albumin (BSA). We observed an increase in the intensity of intrinsic fluorescence for all the flavonols except rutin in the presence of BSA. From the changes in the fluorescence spectra, we concluded that tautomeric forms are formed on interaction with hemoglobin. We determined the interconnection between the structure of related flavonols and their fluorescent properties on interaction with proteins, and we determined the binding constants for binding with BSA and hemoglobin.
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Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 74, No. 5, pp. 659–664, September–October, 2007.
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Sentchouk, V.V., Bondaryuk, E.V. Fluorescent analysis of interaction of flavonols with hemoglobin and bovine serum albumin. J Appl Spectrosc 74, 731–737 (2007). https://doi.org/10.1007/s10812-007-0117-5
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DOI: https://doi.org/10.1007/s10812-007-0117-5