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Spectral-luminescent manifestation of the damaging action of brain ischemia on blood serum components

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Journal of Applied Spectroscopy Aims and scope

Abstract

With the aid of spectral-luminescent analysis, our hypothesis on the determining role of free-radical oxidation in damage of blood serum components (low-density lipoproteins) in ischemia has been confirmed. An increase in the luminescence intensity of the blood serum of animals that suffered from brain ischemia as against that of healthy animals is registered. Lipoperoxide free-radical damage of phospholipids of the amphipathic layer of low-density lipoproteins after an ischemic procedure has also been confirmed by fluorescent probes (rhodamine 6G and Nile Blue).

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Authors and Affiliations

  1. M. V. Lomonosov Moscow State University, Lenisnkie Gory, Moscow, 119992, Russia

    I. M. Vlasova & A. M. Saletskii

Authors
  1. I. M. Vlasova
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  2. A. M. Saletskii
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Correspondence to A. M. Saletskii.

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Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 72, No. 6, pp. 827–831, November–December, 2005.

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Vlasova, I.M., Saletskii, A.M. Spectral-luminescent manifestation of the damaging action of brain ischemia on blood serum components. J Appl Spectrosc 72, 906–910 (2005). https://doi.org/10.1007/s10812-006-0024-1

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  • DOI: https://doi.org/10.1007/s10812-006-0024-1

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