Prevalence of Co-occurring Medical and Behavioral Conditions/Symptoms Among 4- and 8-Year-Old Children with Autism Spectrum Disorder in Selected Areas of the United States in 2010

Abstract

We compared the prevalence of various medical and behavioral co-occurring conditions/symptoms between 4- and 8-year-olds with autism spectrum disorder (ASD) from five sites in the Autism and Developmental Disabilities Monitoring Network during the 2010 survey year, accounting for sociodemographic differences. Over 95% of children had at least one co-occurring condition/symptom. Overall, the prevalence was higher in 8- than 4-year-olds for 67% of co-occurring conditions/symptoms examined. Further, our data suggested that co-occurring conditions/symptoms increased or decreased the age at which children were first evaluated for ASD. Similarly, among the 8-year-olds, the prevalence of most co-occurring conditions/symptoms was higher in children with a previous ASD diagnosis documented in their records. These findings are informative for understanding and screening co-occurring conditions/symptoms in ASD.

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Acknowledgments

We acknowledge CDC ADDM project personnel, ADDM projects coordinators, clinician reviewers, abstractors, data managers, and ADDM investigators at each site who contributed to the ADDM surveillance project and data collection.

Author Contributions

GNS conceptualized the original study, analyzed and interpreted the data, wrote the first manuscript of the article, and approved the final version of the article. MJM, DC, MKS and LAS provided feed-back on the design of the study, interpreted the data, reviewed the different versions of the manuscript, and approved the final version of the manuscript.

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Correspondence to G. N. Soke.

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All procedures performed in studies involving human participants were in accordance with ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study is a secondary data analysis of de-identified data previously collected in a surveillance system. Therefore, formal consent is not required.

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The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

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Soke, G.N., Maenner, M.J., Christensen, D. et al. Prevalence of Co-occurring Medical and Behavioral Conditions/Symptoms Among 4- and 8-Year-Old Children with Autism Spectrum Disorder in Selected Areas of the United States in 2010. J Autism Dev Disord 48, 2663–2676 (2018). https://doi.org/10.1007/s10803-018-3521-1

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Keywords

  • Autism spectrum disorder
  • Autism
  • Prevalence
  • Co-occurring conditions
  • Comorbid conditions