Journal of Autism and Developmental Disorders

, Volume 45, Issue 6, pp 1742–1750

Autism Spectrum Disorder Risk Factors and Autistic Traits in Gender Dysphoric Children

  • Doug P. VanderLaan
  • Jonathan H. Leef
  • Hayley Wood
  • S. Kathleen Hughes
  • Kenneth J. Zucker
Original Paper

Abstract

Gender dysphoria (GD) and autism spectrum disorder (ASD) are associated. In 49 GD children (40 natal males), we examined ASD risk factors (i.e., birth weight, parental age, sibling sex ratio) in relation to autistic traits. Data were gathered on autistic traits, birth weight, parents’ ages at birth, sibling sex ratio, gender nonconformity, age, maternal depression, general behavioral and emotional problems, and IQ. High birth weight was associated with both high gender nonconformity and autistic traits among GD children. Developmental processes associated with high birth weight are, therefore, likely to underlie the GD–ASD link either directly or indirectly. The present study is the first to provide quantitative data bearing on possible mechanisms that lead GD and ASD to co-occur.

Keywords

Gender dysphoria Autism spectrum disorder Birth weight Parental age Sibling sex ratio 

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Doug P. VanderLaan
    • 1
  • Jonathan H. Leef
    • 1
  • Hayley Wood
    • 1
  • S. Kathleen Hughes
    • 1
  • Kenneth J. Zucker
    • 1
    • 2
  1. 1.Gender Identity Service, Child, Youth, and Family Services, Beamish Family WingCentre for Addiction and Mental HealthTorontoCanada
  2. 2.Department of PsychiatryUniversity of TorontoTorontoCanada

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