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Lower Electrodermal Activity to Acute Stress in Caregivers of People with Autism Spectrum Disorder: An Adaptive Habituation to Stress

Journal of Autism and Developmental Disorders volume 45, pages 576–588 (2015)Cite this article

Abstract

Caring for a relative with autism spectrum disorder (ASD) entails being under chronic stress that could alter body homeostasis. Electrodermal activity (EDA) is an index of the sympathetic activity of the autonomic nervous system related to emotionality and homeostasis. This study compares EDA in response to acute stress in the laboratory between parents of people with (n = 30) and without (n = 34) ASD (caregivers and non-caregivers, respectively). Caregivers showed lower EDA in response to acute stress than non-caregivers. They also presented higher trait anxiety, anger, depression, and somatic symptoms than non-caregivers. Higher EDA was related to a worse mood and more severe somatic symptoms only in caregivers. These results could reflect an adaptive habituation to stress and establish that high EDA in response to acute stress depends on caregivers’ health.

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References

  • Baron-Cohen, S., Hoekstra, R. A., Knickmeyer, R., & Wheelwright, S. (2006). The autism spectrum quotient (AQ)—adolescent version. Journal of Autism and Developmental Disorders, 36(3), 343–350. doi:10.1007/s10803-066-0073-6.

    PubMed  Article  Google Scholar 

  • Bayat, M. (2007). Evidence of resilience in families of children with autism. Journal of Intellectual Disability Research, 51(9), 702–714. doi:10.1111/j.1365-2788.2007.00960.x.

    PubMed  Article  Google Scholar 

  • Baztán, J. J., Pérez del Molino, J., Alarcón, T., San Cristóbal, E., Izquierdo, G., & Manzarbeitia, J. (1993). Índice de Barthel: Instrumento válido para la valoración funcional de pacientes con enfermedad cerebrovascular. Revista Española de Geriatria y Gerontologia, 28, 32–40.

    Google Scholar 

  • Beck, A. T., & Steer, R. A. (1993). Beck depression inventory. Manual. San Antonio, TX: The Psychological Corporation.

    Google Scholar 

  • Billings, D., Folkman, S., Acree, M., & Tedlie, J. (2000). Coping and physical health during caregiving: The roles of positive and negative affect. Journal of Personality and Social Psychology, 79(1), 131–142. doi:10.1037//0022-3514.79.1.131.

    PubMed  Article  Google Scholar 

  • Birket-Smith, M., Hasle, N., & Jenses, H. H. (1993). Electrodermal activity in anxiety disorders. Acta Psychiatrica Scandinavica, 88(5), 350–355.

    PubMed  Article  Google Scholar 

  • Bonnet, A., & Naveteur, J. (2004). Electrodermal activity in low back pain patients with and without co-morbid depression. International Journal of Psychophysiology, 59(1), 37–44. doi:10.1016/j.ijpsycho.2004.01.004.

    Article  Google Scholar 

  • Bonnet, A., & Naveteur, J. (2006). Electrodermal responses to words in chronic low back pain patients: A comparison between pain descriptors, other emotional words, and neutral words. The Clinical Journal of Pain, 22(8), 686–691. doi:10.1097/01.ajp.0000210933.66063.ec.

    PubMed  Article  Google Scholar 

  • Boucsein, W. (2012). Electrodermal activity. New York: Plenum Press.

    Book  Google Scholar 

  • Boucsein, W., Fowles, D. C., Grimnes, S., Ben-Shakhar, G., Roth, W. T., Dawson, M. E., et al. (2012). Publication recommendations for electrodermal measurements. SPR ad hoc committee for electrodermal measures. Psychophysiology, 49(8), 1017–1034. doi:10.1111/j.1469-8986.2012.01384.x.

    PubMed  Google Scholar 

  • Carrillo, E., Moya-Albiol, L., González-Bono, E., Salvador, A., Ricarte, J., & Gómez-Amor, J. (2001). Gender differences in cardiovascular and electrodermal responses to public speaking task: the role of anxiety and mood states. International Journal of Psychophysiology, 42(3), 253–264. doi:10.1016/S0167-8760(01)00147-7.

    PubMed  Article  Google Scholar 

  • Chida, Y., & Hamer, M. (2008). Chronic psychosocial factors and acute physiological responses to laboratory-induced stress in healthy populations: A quantitative review of 30 years of investigations. Psychological Bulletin, 134(6), 829–885. doi:10.1037/a0013342.

    PubMed  Article  Google Scholar 

  • Critchley, H. D. (2002). Electrodermal responses: What happens in the brain. Neuroscientist, 8(2), 132–142. doi:10.1177/107385840200800209.

    PubMed  Article  Google Scholar 

  • Davis, N. O., & Carter, A. S. (2008). Parenting stress in mothers and fathers of toddlers with autism spectrum disorders: Associations with child characteristics. Journal of Autism and Developmental Disorders, 38(7), 1278–1291. doi:10.1007/s10803-007-0512-z.

    PubMed  Article  Google Scholar 

  • De Andrés-García, S., Moya-Albiol, L., González-Bono, E. (2012). Salivary cortisol and immunoglobulin A: Responses to stress as predictors of health complaints reported by caregivers of offspring with autistic spectrum disorder. Hormones and Behavior, 62(4), 464–474. doi:10.1016/j.yhbeh.2012.08.003.

  • Dickerson, S. S., & Kemeny, M. E. (2004). Acute stressors and cortisol responses: A theoretical integration and synthesis of laboratory research. Psychological Bulletin, 130(3), 355–391.

    PubMed  Article  Google Scholar 

  • El-Sheikh, M., & Arsiwalla, D. D. (2011). Children’s sleep, skin conductance level and mental health. Journal of Sleep Research, 20(2), 326–337. doi:10.1111/j.1365-2869.2010.00880.x.

    PubMed  Article  Google Scholar 

  • Endicott, J., Spitzer, R. L., Fleiss, J. L., & Cohen, J. (1976). The global assessment scale: A procedure for measuring overall severity of psychiatric disturbance. Archives of General Psychiatry, 33(6), 766–771. doi:10.1001/archpsyc.1976.01770060086012.

    PubMed  Article  Google Scholar 

  • Estes, A., Munson, J., Dawson, G., Koehler, E., Zhou, X. H., & Abbott, R. (2009). Parenting stress and psychological functioning among mothers of preschool children with autism and developmental delay. Autism, 13(4), 375–387. doi:10.1177/1362361309105658.

    PubMed  Article  Google Scholar 

  • Estes, A., Olson, E., Sullivan, K., Greenson, J., Winter, J., Dawson, G., et al. (2013). Parenting-related stress and psychological distress in mothers of toddlers with autism spectrum disorders. Brain and Development, 35(2), 133–138. doi:10.1016/j.braindev.2012.10.004.

    PubMed Central  PubMed  Article  Google Scholar 

  • Fowles, D. C. (2000). Electrodermal hyporeactivity and antisocial behavior: Does anxiety mediate the relationship? Journal of Affective Disorders, 61(3), 177–189. doi:10.1016/S0165-0327(00)00336-0.

    PubMed  Article  Google Scholar 

  • Fowles, D. C., Christie, M. J., Edelberg, R., Grings, W. W., Lykken, D. T., & Venables, P. H. (1981). Committee report. Publication recommendations for electrodermal measurements. Psychophysiology, 18(3), 232–239.

    PubMed  Article  Google Scholar 

  • Fuentes, I., Balaguer, I., Meliá, J. & García-Merita, M. (1995). Forma abreviada del Perfil de Estados de Animo (POMS). In E. Cantó n (Ed.), Libro de Actas del V Congreso Nacional de Psicologia de la Actividad Física y el Deporte. Valencia, Spain: Universitat de Valéncia.

  • Gonçalves, T., & Graça, M. (2011). Variables fisiológicas y sobrecarga familiar en hijos de enfermos oncológicos. Revista Argentina de Clínica Psicológica, 20(3), 255–263.

    Google Scholar 

  • González-Bono, E., Moya-Albiol, L., Salvador, A., Carrillo, E., Ricarte, J., & Gómez-Amor, J. (2002). Anticipatory autonomic response to a public speaking task in women: the role of trait anxiety. Biological Pshychology, 60(1), 37–49. doi:10.1016/S0301-0511(02)00008-X.

    Article  Google Scholar 

  • Hastings, R. P. (2002). Parental stress and behaviour problems of children with developmental disability. Journal of Intellectual and Developmental Disability, 27(3), 149–160. doi:10.1080/1366825021000008657.

    Article  Google Scholar 

  • Hugdahl, K. (1995). Psychophysiology: The mind-body perspective. United States: Harvard University Press.

    Google Scholar 

  • Juárez, F., Castro, G., & Scarpeta, D. (2005). Oscilaciones en la actividad electrodérmica y en el flujo sanguíneo periférico y estado de salud. Psicología y salud, 15(2), 285–294.

    Google Scholar 

  • Khanna, R., Madhavan, S. S., Smith, M. J., Patrick, J. H., Tworek, C., & Becker-Cottrill, B. (2011). Assessment of health-related quality of life among primary caregivers of children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 41(9), 1214–1227. doi:10.1007/s10803-010-1140-6.

    PubMed  Article  Google Scholar 

  • Kirschbaum, C., Pirke, K. M., & Hellhammer, D. H. (1993). The ‘Trier Social Stress Test’ a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology, 28(1–2), 76–81. doi:10.1159/000119004.

    PubMed  Article  Google Scholar 

  • Kreibig, S. D. (2010). Autonomic nervous system activity in emotion: A review. Biological Psychology, 84(3), 394–421. doi:10.1016/j.biopsycho.2010.03.010.

    PubMed  Article  Google Scholar 

  • Kudielka, B. M., Buske-Kirschbaum, A., Hellhammer, D. M., & Kirschbaum, C. (2004). Differential heart rate reactivity and recovery after psychosocial stress (TSST) in healthy children, younger adults and elderly adults: The impact of age and gender. International Journal of Behavioral Medicine, 11(2), 116–121. doi:10.1207/s15327558ijbm1102_8.

    PubMed  Article  Google Scholar 

  • Lazarus, R. S. (1991). Emotion and adaptation. New York: Oxford University Press.

    Google Scholar 

  • Lensvelt-Mulders, G., & Hettema, J. (2001). Genetic analysis of autonomic reactivity to psychologically stressful situations. Biological Psychology, 58(1), 25–40. doi:10.1016/S0301-0511(01)00099-0.

    PubMed  Article  Google Scholar 

  • Mardaga, H., & Hansenne, M. (2009). Autonomic aspect of emotional response in depressed patients: Relationships with personality. Clinical Neurophysiology, 39(4), 209–216. doi:10.1016/j.neucli.2009.06.002.

    PubMed  Article  Google Scholar 

  • Martínez-Selva, J. M., Gómez-Amor, J., Olomos, E., Navarro, N., & Román, F. (1987). Sex and menstrual cycle differences in the habituation and spontaneous recovery of the electrodermal orienting reaction. Personality and Individual Differences, 8(2), 211–217. doi:10.1016/0191-8869(87)90176-0.

    Article  Google Scholar 

  • McEwen, B. S. (2007). Physiology and neurobiology of stress and adaptation: Central role of the brain. Physiological Review, 87(3), 873–904. doi:10.1152/physrev.00041.2006.

    Article  Google Scholar 

  • Miguel-Tobal, J. J., Casado, M. I., Cano-Vindel, A., & Spielberger, C. D. (2001). Inventario de Expresion de Ira Estado-Rasgo: STAXI-2. Madrid: TEA Ediciones.

    Google Scholar 

  • Miquel, M., Fuentes, I., García-Merita, M., & Rojo, L. (1999). Habituation and sensitization processes in depressive disorders. Psychopathology, 32(1), 35–42.

    PubMed  Article  Google Scholar 

  • Moya-Albiol, L., De Andrés-García, S., Sanchis-Calatayud, M. V., Sariñana-González, P., Ruiz-Robledillo, N., Romero-Martínez, A., et al. (2013). Psychophysiological responses to cooperation: The role of outcome and gender. International Journal of Psychology, 48(4), 542–550. doi:10.1080/00207594.2012.666552.

    PubMed  Article  Google Scholar 

  • Moya-Albiol, L., Salvador, A., Costa, R., Martínez-Sanchís, S., & González-Bono, S. (2003). Psychophysiological responses to acute stress in two groups of healthy women differing in fitness. Psicothema, 15(4), 563–568.

    Google Scholar 

  • Moya-Albiol, L., Salvador, A., Costa, R., Martínez-Sanchis, S., González-Bono, E., Ricarte, J., et al. (2001a). Psychophysiological responses to the Stroop Task after a maximal cycle ergometry in elite sportsmen and physically active subjects. International Journal of Psychophysiology, 40(1), 47–59. doi:10.1016/S0167-8760(00)00125-2.

    PubMed  Article  Google Scholar 

  • Moya-Albiol, L., Salvador, A., González-Bono, S., Martínez-Sanchís, S., & Costa, R. (2001b). The impact of exercise on hormones is related to autonomic reactivity to a mental task. International Journal of Stress Management, 8(3), 215–229. doi:10.1023/A:1011391109602.

    Article  Google Scholar 

  • Naveteur, J., Buisine, S., & Gruzelier, J. H. (2005). The influence of anxiety on electrodermal responses to distractors. International Journal of Psychophysiology, 56(3), 261–269. doi:10.1016/j.ijpsycho.2004.12.006.

    PubMed  Article  Google Scholar 

  • Naveteur, J., & Roy, J. C. (1990). Electrodermal activity of low and high trait anxiety subjects during a frustrative video game. Journal of Psychophysioly, 4(3), 221–227.

    Google Scholar 

  • Nilsson, B. M., Hultman, C. M., & Wiessel, F. A. (2006). Niacin skin-flush response and electrodermal activity in patients with schizophrenia and healthy controls. Prostaglandins Leukotrienes and Essential Fatty Acids, 74(5), 339–346. doi:10.1016/j.plefa.2006.02.002.

    Article  Google Scholar 

  • Papousek, I., Schulter, G., & Premsberger, E. (2002). Dissociated autonomic regulation during stress and physical complaints. Journal of Psychosomatic Research, 52(4), 257–266. doi:10.1016/S0022-3999(02)00298-2.

    PubMed  Article  Google Scholar 

  • Patrick, C. J. (2008). Psychophysiological correlates of aggression and violence: An integrative review. Transactions of the Royal Society B, 363(1503), 2543–2555. doi:10.1098/rstb.2008.0028.

    Article  Google Scholar 

  • Peters, M. L., & Schmidt, J. M. (1991). Psychophysiological responses to repeated acute pain stimulation in chronic low back pain patients. Journal of Psychosomatic Research, 35(1), 59–74. doi:10.1016/0022-3999(91)90007-B.

    PubMed  Article  Google Scholar 

  • Putnam, L. E., Johnson, R, Jr, & Roth, W. T. (1992). Guidelines for reducing the risk of disease transmission in the psychophysiology laboratory. SPR ad hoc committee on the prevention of disease transmission. Psychophysiology, 29(2), 127–141.

    PubMed  Article  Google Scholar 

  • Roseman, I. J., & Smith, C. A. (2001). Appraisal theory: Overview, assumptions, varieties, controversies. In K. R. Scherer, A. Schorr, T. Johnstone (Ed.), Appraisal processes in emotion: Theory, methods. research (pp. 3–19). New York: Oxford University Press.

  • Ruiz-Robledillo, N., & Moya-Albiol, L. (2013). Self-reported health and cortisol awakening response in parents of people with asperger syndrome: The role of trait anger and anxiety, coping and burden. Psychology and Health, 28(11), 1246–1264. doi: 10.1080/08870446.2013.800517.

  • Salovey, P., Detweiler, J., Steward, W., & Rothman, A. (2000). Emotional states and physical health. American Psychologist, 55(1), 110–121. doi:10.1037/0003-066X.55.1.110.

    PubMed  Article  Google Scholar 

  • Sandín, B., & Chorot, P. (1995). Escala de Síntomas Somáticos-Revisada (ESS-R). Madrid: Universidad Nacional de Educación a Distancia (UNED).

    Google Scholar 

  • Scarpa, A., & Raine, A. (1997). Psychophysiology of anger and violent behavior. Psychiatric Clinics of North America, 20(2), 375–394. doi:10.1016/S0193-953X(05)70318-X.

    PubMed  Article  Google Scholar 

  • Schwerdtfeger, A., & Rosenkaimer, A. K. (2011). Depressive symptoms and attenuated physiological reactivity to laboratory stressors. Biological Psyhology, 87(3), 430–438. doi:10.1016/j.biopsycho.2011.05.

    Article  Google Scholar 

  • Seisdedos, N. (1982). STAI: Inventario de Ansiedad Estado-Rasgo [State-Trait Anxiety Inventory]. Madrid: TEA Ediciones.

    Google Scholar 

  • Seltzer, M. M., Greenberg, J. S., Hong, J., Smith, L. E., Almeida, D. M., Coe, C., et al. (2010). Maternal cortisol levels and behavior problems in adolescents and adults with ASD. Journal of Autism and Developmental Disorders, 40(4), 457–469. doi:10.1007/s10803-009-0887-0.

    PubMed Central  PubMed  Article  Google Scholar 

  • Smith, L. E., Hong, J., Seltzer, M. M., Greenberg, J. S., Almeida, D. M., & Bishop, S. L. (2010). Daily experiences among mothers of adolescents and adults with Autism Spectrum Disorder. Journal of Autism and Developmental Disabilities, 4(2), 167–178. doi:10.1007/s10803-009-0844-y.

    Article  Google Scholar 

  • Smith, L. E., Seltzer, M. M., & Greenberg, J. S. (2012). Daily health symptoms of mothers of adolescents and adults with fragile x syndrome and mothers of adolescents and adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 42(9), 1836–1846. doi:10.1007/s10803-011-1422-7.

    PubMed Central  PubMed  Article  Google Scholar 

  • Smith, L. E., Seltzer, M. M., Tager-Flusberg, H., Greenberg, J. S., & Carter, A. S. (2008). A comparative analysis of well-being and coping among mothers of toddlers and mothers of adolescents with ASD. Journal of Autism and Developmental Disorders, 38(5), 876–889.

    PubMed Central  PubMed  Article  Google Scholar 

  • Soares, A. J. (2009). Variáveis Psicossociais e Reactividade Emocional em Cuidadores de Dependentes de Substâncias.Unpublished doctoral dissertation. University of Minho, Minho, Portugal.

  • Spielberger, C.D., Gorusch, R.L., Lushene, R., Vagg, P.R. and Jacobs, G.A. (1983). Manual for the state-trait anxiety inventory. Consulting Psychologists Press.

  • Thompson, R. L., Lewis, S. L., Murphy, M. R., Hale, J. M., Blackwell, P. H., Acton, G. J., et al. (2004). Are there sex differences in emotional and biological responses in spousal caregivers of patients with Alzheimer’s disease? Biological Research for Nursing, 5(4), 319–330. doi:10.1177/1099800404263288.

    PubMed  Article  Google Scholar 

  • Thorell, L. H., Kjellman, B., & D’Elia, G. (1987). Electrodermal activity in relation to diagnostic subgroups and symptoms of depressive patients. Acta Psychiatrica Scandinavica, 76(6), 693–701. doi:10.1111/j.1600-0447.1987.tb02941.x.

    PubMed  Article  Google Scholar 

  • Venables, P. H., & Mitchell, D. A. (1996). The effects of age, sex and time of testing on skin conductance activity. Biological Psychology, 43(2), 87–101. doi:10.1016/0301-0511(96)05183-6.

    PubMed  Article  Google Scholar 

  • Wilken, J. A., Smith, B. D., Tola, K., & Mann, M. (2000). Trait anxiety and prior exposure to non-stressful stimuli: effects on psychophysiological arousal and anxiety. International Journal of Psychophysiololgy, 37(3), 233–242. doi:10.1016/S0167-8760(00)00082-9.

    Article  Google Scholar 

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Acknowledgments

This study was financed by the Spanish Ministry of Science and Innovation (PSI2008-0448/PSIC), and the Committee for Business, Research, and Science of the Regional Government of Valencia, research groups and networks of excellence (ACOMP/2010/250; PROMETEO/2011/048; ISIC/2013/001). This research is part of the doctoral dissertation project of the first author, financed by the University of Valencia (“Atracció de Talents” VLC-CAMPUS 2011). Authors also wish to thank “INC Servicios Lingüísticos” and John Rawlins for the revision of the English text.

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  1. Department of Psychobiology, Faculty of Psychology, University of Valencia, Av. Blasco Ibáñez, 21, 46010, Valencia, Spain

    Nicolás Ruiz-Robledillo & Luis Moya-Albiol

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  1. Nicolás Ruiz-Robledillo
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Correspondence to Luis Moya-Albiol.

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Ruiz-Robledillo, N., Moya-Albiol, L. Lower Electrodermal Activity to Acute Stress in Caregivers of People with Autism Spectrum Disorder: An Adaptive Habituation to Stress. J Autism Dev Disord 45, 576–588 (2015). https://doi.org/10.1007/s10803-013-1996-3

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Keywords

  • Electrodermal activity
  • Caregivers
  • Autism spectrum disorder
  • Autonomic nervous system
  • Health