Cortisol Responsivity Differences in Children with Autism Spectrum Disorders During Free and Cooperative Play
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Children with autism spectrum disorder (ASD) demonstrate significant heterogeneity in their profiles of social interaction and stress responsivity. We evaluated behavior and stress response in 52 male children ages 8–12 in a naturalistic playground interaction paradigm involving a child with ASD, a typically developing peer, and a same-age confederate. Younger children in the ASD group engaged in 5.8 times more approach behavior and showed a lower cortisol response than their older peers. Those that verbally initiated with their peers also showed a higher cortisol response. Older children with ASD exhibited the highest stress responsivity, while younger children with ASD showed more willingness to approach others without apparent stress. Intervening early and often may contribute to improvements in social engagement in youth with ASD.
KeywordsAutism Cortisol Play Social Stress Responder
This work was supported in part by National Institute of Health R01 MH085717 awarded to Blythe Corbett. Portions of these data were completed as part of Clayton Schupp’s dissertation. We are grateful to the children and families who continue to support our research.
Conflict of interest
The authors declare that they have no conflicts of interest.
- APA. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text revision) (DSM-IV-TR). Washington, DC: American Psychiatric Association.Google Scholar
- Chandler, S., Charman, T., Baird, G., Simonoff, E., Loucas, T., Meldrum, D., et al. (2007). Validation of the social communication questionnaire in a population cohort of children with autism spectrum disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 46(10), 1324–1332.PubMedCrossRefGoogle Scholar
- Fitzmaurice, G., Laird, N., & Ware, J. (2004). Applied longitudinal analysis. London: Wiley.Google Scholar
- Hennessy, J. W., & Levine, S. (1979). Stress, arousal, and the pituitary-adrenal system: A psychoendocrine hypothesis. In: J. M. Sprague & A. N. Epstein (Eds.), Progress in Psychobiology and Physiological Psychology (8th ed., pp. 133–178). New York: Academic Press.Google Scholar
- Jansen, L. M., Gispen-de Wied, C. C., Wiegant, V. M., Westenberg, H. G., Lahuis, B. E., & van Engeland, H. (2006). Autonomic and neuroendocrine responses to a psychosocial stressor in adults with autistic spectrum disorder. Journal of Autism and Developmental Disorders, 36(7), 891–899.PubMedCrossRefGoogle Scholar
- Lieberman, R. G., & Yoder, P. (2012). Play and communication in children with autism spectrum disorder: A framework for early intervention. Journal of Early Intervention, 34(2), 82–103.Google Scholar
- Lopata, C., Volker, M. A., Putnam, S. K., Thomeer, M. L., & Nida, R. E. (2008). Effect of social familiarity on salivary cortisol and self-reports of social anxiety and stress in children with high functioning autism spectrum disorders. Journal of Autism and Developmental Disorders, 38(10), 1866–1877.PubMedCrossRefGoogle Scholar
- Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Jr, Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223.PubMedCrossRefGoogle Scholar
- Lord, C., Rutter, M., DiLavore, P., & Risi, S. (1999). Autism diagnostic observation schedule-WPS. Los Angeles, CA: Western Psychological Services.Google Scholar
- Lyons, D., Mason, W. A., & Mendoza, S. P. (1990). Beyond the ethogram: Transactional analysis of behavior in primate social interchanges. American Journal of Primatology, 20, 209.Google Scholar
- Mason, W., Long, D., & Mendoza, S. (1993). Temperment and mother–infant conflict in macaques: A transactional analysis. In W. M. S. Mendoza (Ed.), Primate social conflict (pp. 205–227). Albany, NY: SUNY Press.Google Scholar
- Noldus. (2008). The Observer XT (Vol. 10.5). Wageningen: Noldus Information Technology.Google Scholar
- Pinheiro, J., Bates, D., DebRoy, S., Sarkar, D., & R Development Core Team. (2012). nlme: Linear and nonlinear mixed effects models. R package version 3.1-105.Google Scholar
- R Core Team. (2012). R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing. http://www.R-project.org/.
- Rutter, M., Bailey, A., & Lord, C. (2003). The Social Communication Questionnaire. Los Angeles, CA: Western Psychological Services.Google Scholar
- Wechsler, D. (1999). Wechsler abbreviated scale of intelligence. San Antonio, TX: Psychological Corporation.Google Scholar
- White, S. W., Albano, A. M., Johnson, C. R., Kasari, C., Ollendick, T., Klin, A., et al. (2010). Development of a cognitive-behavioral intervention program to treat anxiety and social deficits in teens with high-functioning autism. Clinical Child Family Psychology Review, 13(1), 77–90.PubMedCrossRefGoogle Scholar