Journal of Autism and Developmental Disorders

, Volume 40, Issue 9, pp 1080–1093 | Cite as

Comorbid Psychiatric Disorders Associated with Asperger Syndrome/High-functioning Autism: A Community- and Clinic-based Study

  • Marja-Leena Mattila
  • Tuula Hurtig
  • Helena Haapsamo
  • Katja Jussila
  • Sanna Kuusikko-Gauffin
  • Marko Kielinen
  • Sirkka-Liisa Linna
  • Hanna Ebeling
  • Risto Bloigu
  • Leena Joskitt
  • David L. Pauls
  • Irma Moilanen
Original Paper

Abstract

The present study identifies the prevalence and types of comorbid psychiatric disorders associated with Asperger syndrome (AS)/high-functioning autism (HFA) in a combined community- and clinic-based sample of fifty 9- to 16-year-old subjects using the Schedule for Affective Disorders and Schizophrenia for School-Age Children, Present and Lifetime Version. The level of functioning was estimated using the Children’s Global Assessment Scale. The results support common (prevalence 74%) and often multiple comorbid psychiatric disorders in AS/HFA; behavioral disorders were shown in 44%, anxiety disorders in 42% and tic disorders in 26%. Oppositional defiant disorder, major depressive disorder and anxiety disorders as comorbid conditions indicated significantly lower levels of functioning. To target interventions, routine evaluation of psychiatric comorbidity in subjects with AS/HFA is emphasized.

Keywords

Comorbidity CGAS Asperger syndrome Autism Pervasive developmental disorders Autism spectrum disorders 

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Marja-Leena Mattila
    • 1
  • Tuula Hurtig
    • 1
    • 2
  • Helena Haapsamo
    • 1
  • Katja Jussila
    • 1
  • Sanna Kuusikko-Gauffin
    • 1
  • Marko Kielinen
    • 3
  • Sirkka-Liisa Linna
    • 1
    • 2
  • Hanna Ebeling
    • 1
  • Risto Bloigu
    • 4
  • Leena Joskitt
    • 1
  • David L. Pauls
    • 5
  • Irma Moilanen
    • 1
  1. 1.Clinic of Child Psychiatry, University Hospital of OuluUniversity of OuluOuluFinland
  2. 2.Institute of Health SciencesUniversity of OuluOuluFinland
  3. 3.Department of Educational Sciences and Teacher EducationUniversity of OuluOuluFinland
  4. 4.Medical Informatics GroupUniversity of OuluOuluFinland
  5. 5.Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General HospitalHarvard Medical SchoolBostonUSA

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