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Motor Signs Distinguish Children with High Functioning Autism and Asperger’s Syndrome from Controls

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Abstract

While many studies of motor control in autism have focused on specific motor signs, there has been a lack of research examining the complete range of subtle neuromotor signs. This study compared performance on a neurologic examination standardized for children (PANESS, Physical and Neurological Exam for Subtle Signs, Denckla [1974 Developmental Medicine and Child Neurology, 16(6), 729–741]) between a group of 40 boys aged 6–17 with autism and average range IQs and a group of 55 typically developing boys. The Autism group was shown to have significant impairment on several measures of motor control compared to the Control group. Regression analyses revealed that a model including four PANESS variables offered a high level of discrimination in distinguishing boys with high-functioning autism from controls.

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References

  • American Psychiatric Association (APA) (1994). Diagnostic and statistical manual of mental disorders, 4th edn. Washington, DC.

  • Bruininks, R. H. (1978). The Bruininks–Oseretsky test of motor proficiency. Circle Pines, MN: American Guidance Service.

    Google Scholar 

  • Cox, A. D. (1991). Is Asperger’s syndrome a useful diagnosis? Archives of Disease in Childhood, 66, 259–262.

    PubMed  Google Scholar 

  • Denckla, M. B. (1974). Development of motor co-ordination in normal children. Developmental Medicine and Child Neurology, 16(6), 729–741.

    Article  PubMed  Google Scholar 

  • Denckla, M. B., & Rudel, R. G. (1978). Anomalies of motor development in hyperactive boys. Annals of Neurology, 3(3), 231–233.

    Article  PubMed  Google Scholar 

  • Denckla, M. B., Rudel, R.G., Chapman, C., & Krieger, J. (1985). Motor proficiency in dyslexic children with and without attentional disorders. Archives of Neurology, 42, 228–231.

    PubMed  Google Scholar 

  • Firth, U. (1991). Autism and Asperger syndrome. Cambridge, UK: Cambridge University Press.

    Google Scholar 

  • Ghaziuddin, M., & Butler, E. (1998). Clumsiness in autism and Asperger syndrome: A further report. Journal of Intellectual Disability Research, 42, 43–48.

    Article  PubMed  Google Scholar 

  • Ghaziuddin, M., Butler, E., Tsai, L.Y., & Ghaziuddin, N. (1994). Is clumsiness a marker for Asperger syndrome? Journal of Intellectual Disability Research, 38, 519–527.

    Article  PubMed  Google Scholar 

  • Ghaziuddin, M., Tsai, L. Y., & Ghaziuddin, N. (1992). A reappraisal of clumsiness as a diagnostic feature of Asperger syndrome. Journal of Autism and Developmental Disorders, 22, 651–656.

    Article  PubMed  Google Scholar 

  • Gillberg, C. (1992). The Emanuel Miller Memorial Lecture 1991: Autism and autistic-like conditions: Subclasses among disorders of empathy. Journal of Psychology and Psychiatry, 33, 813–842.

    Article  Google Scholar 

  • Green, D., Baird, G., Barnett, A. L., Henderson, L., Huber, J., & Henderson, S. E. (2002). The severity and nature of motor impairment in Asperger’s syndrome: A comparison with specific developmental disorder of motor function. Journal of Child Psychology and Psychiatry, 43(5), 655–668.

    Article  PubMed  Google Scholar 

  • Hallett, M., Lebiedowska, M. K., Thomas, S. L., Stanhope, S. J., Denckla, M. B., & Runsey, J. (1993). Locomotion of autistic adults. Archives of Neurology, 50(12), 1304–1308.

    PubMed  Google Scholar 

  • Henderson, S. E., & Sugden, D. A. (1992). Movement assessment battery for children. London: Psychological Corporation.

    Google Scholar 

  • Hocking, R. R. (1976). The analysis and selection of variables in linear regression. Biometrics, 32, 1–49.

    Article  Google Scholar 

  • Holden, E. W., Tarnowski, K. J., & Prinz, R. J. (1982). Reliability of neurological soft signs in children: Reevaluation of the PANESS. Journal of Abnormal Child Psychology, 10(2), 163–172.

    Article  PubMed  Google Scholar 

  • Hosmer, D. W., Jovanovic B., Lemeshow S. (1989). Best subsets logistic regression. Biometrics, 45, 1265–1270.

    Article  Google Scholar 

  • Hughes, C. (1996). Brief report: Planning problems in autism at the level of motor control. Journal of Autism and Developmental Disorders, 26, 99–108.

    Article  PubMed  Google Scholar 

  • Jones, V., & Prior, M. (1985). Motor imitation abilities and neurological signs in autistic children. Journal of Autism and Developmental Disorders, 15(1), 37–46.

    Article  PubMed  Google Scholar 

  • Kadesjo, B., & Gillberg, C. (1998). Attention deficits and clumsiness in Swedish 7-year-old children. Developmental Medicine and Child Neurology, 40, 796–804.

    Article  PubMed  Google Scholar 

  • Knights, R. M., & Norwood, J. A. (1979). Revised smoothed normative data on the neuropsychological test battery for children. Ottawa, Ontario, Canada: Dept. of Psychology, Carleton University.

    Google Scholar 

  • Kroes, M., Kessels, A.G., Kalff, A. C., Feron, F. J., Vissers, Y. L., Jolles, J., & Vles, J. S. (2002). Quality of movement as predictor of ADHD: Results from a prospective population study in 5- and 6-year-old children. Developmental Medicine and Child Neurology, 44(11), 753–760.

    Article  PubMed  Google Scholar 

  • Lord, C., Rutter, M., Goode, S., Heemsbergen J., Jordan H., Mawhood L., & Schopler, E. (1989). Autism diagnostic observation schedule: A standardized observation of communication and social behavior. Journal of Autism and Developmental Disorders, 19, 185–212.

    Article  PubMed  Google Scholar 

  • Lord, C., Risi, S., Lambrecht, L., Cook, E. H. Jr., Levanthal, B. L., DiLavore, P. C., Pickles, A., & Rutter, M. (2000). The autism diagnostic observation schedule – generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223.

    Article  PubMed  Google Scholar 

  • Lord, C., Rutter, M., & LeCouteur, A. (1994). Autism diagnostic interview revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685.

    Article  PubMed  Google Scholar 

  • Manjiviona, J., & Prior, M. (1995). Comparison of Asperger syndrome and high-functioning autistic children on a test of motor impairment. Journal of Autism and Developmental Disorders, 25, 23–29.

    Article  PubMed  Google Scholar 

  • Mawson, D., Grounds, A., & Tantam, D. (1985). Violence and Asperger’s syndrome: A case study. British Journal of Psychiatry, 147, 566–569.

    Article  PubMed  Google Scholar 

  • Miyahara, M., Tsujii, M., Hori, M., Nakanishi, K., Kageyama, H., & Sugiyama, T. (1997). Brief report: Motor incoordination in children with Asperger’s syndrome and learning disabilities. Journal of Autism and Developmental Disorders, 27, 595–603.

    Article  PubMed  Google Scholar 

  • Mostofsky, S. H., & Denckla, M. B. (2002). Excessive overflow movements on neurologic examination in children with ADHD. Annals of Neurology, 52, S127.

    Article  Google Scholar 

  • Mostofsky, S. H., Goldberg, M. C., Landa, R. J., & Denckla, M. B. (2000). Evidence for a deficit in procedural learning in children and adolescents with autism: Implications for cerebellar contribution. Journal of the International Neuropsychological Society, 6, 752–759.

    Article  PubMed  Google Scholar 

  • Müller, R. A., Pierce, K., Ambrose, J. B., Allen, G., & Courchesne, E. (2001). Atypical patterns of cerebral motor activation in autism: A functional magnetic resonance study. Biological Psychiatry, 49, 665–676.

    Article  PubMed  Google Scholar 

  • Piek, J. P., Pitcher, T. M., & Hay, D. A. (1999). Motor coordination and kinaesthesis in boys with attention deficit-hyperactivity disorder. Developmental Medicine and Child Neurology, 41, 159–165.

    Article  PubMed  Google Scholar 

  • Reich, W., Welner, Z., & Herjanic, B. (1997). The diagnostic interview for children and adolescents-IV. North Tonawanda: Multi-Health Systems.

    Google Scholar 

  • Rinehart, N. J., Bradshaw, J. L., Brereton, A. V., & Tonge, B. J. (2001). Movement preparation in high-functioning autism and Asperger disorder: A serial choice reaction time task involving motor reprogramming. Journal of Autism and Developmental Disorders, 31(1), 79–88.

    Article  PubMed  Google Scholar 

  • Schuerholz, L. J., Cutting, L., Mazzocco, M. M. M., Singer, H. S., & Denckla, M. B. (1997). Neuromotor functioning in children with Tourette syndrome with and without attention deficit hyperactivity disorder. Journal of Child Neurology, 12(7), 438–442.

    Article  PubMed  Google Scholar 

  • Smith, I. M., & Bryson, S. E. (1994). Imitation and action in autism: A critical review. Psychological Bulletin, 116(2), 259–273.

    Article  PubMed  Google Scholar 

  • Steger, J., Imhof, K., Coutts, E., Gundelfinger, R., Steinhausen, H. C., & Brandeis, D. (2001). Attentional and neuromotor deficits in ADHD. Developmental Medicine and Child Neurology, 43, 172–179.

    Article  PubMed  Google Scholar 

  • Stott, D. H., Moyes, F. A., & Henderson, S. E. (1984). Manual: Test of motor impairment (Henderson Revision). Guelph: Brook International.

  • Szatmari, P., Tuff, L., Finlayson, A. J., & Bartolucci, G. (1990). Asperger’s syndrome and autism: Neurocognitive aspects. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 130–136.

    Article  PubMed  Google Scholar 

  • Szatmari, P., Archer, L., Fisman, S., Streiner, D. L., & Wilson, F. (1995). Asperger’s syndrome and autism: Differences in behavior, cognition, and adaptive functioning. Journal of American Academy of Child and Adolescent Psychiatry, 34, 1662–1671.

    Article  Google Scholar 

  • Vilensky, J. A., Damasio, A. R., & Maurer, R. G. (1981). Gait disturbances in patients with autistic behavior: A preliminary study. Archives of Neurology, 38(10), 646–649.

    PubMed  Google Scholar 

  • Wechsler, D. (1974). Wechsler intelligence scale for children – revised. San Antonio, TX: The Psychological Corporation.

    Google Scholar 

  • Wechsler, D. (1981). Wechsler adult intelligence scale – revised. San Antonio, TX: The Psychological Corporation.

    Google Scholar 

  • Wechsler, D. (1991). Wechsler intelligence scale for children – III. San Antonio, TX: The Psychological Corporation.

    Google Scholar 

  • World Health Organization. (1993). The ICD-10: DCR-10. Classification of mental and behavioural disorders: Diagnostic criteria for research. Geneva: World Health Organization.

    Google Scholar 

Download references

Acknowledgments

This study was supported by grants from the National Alliance for Autism Research, the Rita Rudel Foundation, CDC U10/CCU320408 (to CJN) and NIH: K08 NS02039, K02 NS44850, and R01 NS048527 (to SHM), K01MH01824 (to MCG), DAM D17-00-1-0548, P30 HD240614P50, NS 353359, MH 52432R29, and P01 HD35468

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Authors and Affiliations

  1. Georgia State University, Atlanta, GA, USA

    Eva M. Jansiewicz

  2. Department of Psychiatry, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Melissa C. Goldberg & Rebecca Landa

  3. Johns Hopkins University School of Public Health, Baltimore, MD, USA

    Craig J. Newschaffer

  4. Departments of Neurology, Psychiatry, and Pediatrics, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Martha B. Denckla

  5. Departments of Neurology and Psychiatry, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, 707 N. Broadway, Ste. 516, Baltimore, MD, USA

    Stewart H. Mostofsky

Authors
  1. Eva M. Jansiewicz
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  2. Melissa C. Goldberg
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  3. Craig J. Newschaffer
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  4. Martha B. Denckla
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  5. Rebecca Landa
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  6. Stewart H. Mostofsky
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Correspondence to Stewart H. Mostofsky.

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Jansiewicz, E.M., Goldberg, M.C., Newschaffer, C.J. et al. Motor Signs Distinguish Children with High Functioning Autism and Asperger’s Syndrome from Controls. J Autism Dev Disord 36, 613–621 (2006). https://doi.org/10.1007/s10803-006-0109-y

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