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Brief Report: Acrocallosal Syndrome and Autism

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Abstract

The authors describe a boy presenting with acrocallosal syndrome and autism. Clinical features included craniofacial dysmorphisms, polydactyly, and mental retardation, besides behavioral symptoms compatible with autism. Neuroimaging revealed hypoplasia of the corpus callosum and cerebellar abnormalities. The role of this entity and other associated conditions in autism may be coincidental or reveal new clues to the understanding of autism as a behavioral syndrome.

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References

  • M.L. Berthier (1994) ArticleTitleCorticocallosal anomalies in Asperger’s syndrome American Journal of Roentgenology 162 236–237

    Google Scholar 

  • M.L. Buyse (1990) Birth defects encyclopedia Blackwell Scientific Publications Dover

    Google Scholar 

  • E. Courchesne G.A. Press R. Yeung-Courchesne (1993) ArticleTitleParietal lobe abnormalities detected with MR in patients with infantile autism American Journal of Roentgenology 160 387–393

    Google Scholar 

  • E. Courchesne O. Saitoh R. Yeung-Courchesne G.A. Press A.J. Lincoln R.H. Haas L. Schreibman (1994) ArticleTitleAbnormality of cerebellar vermian lobules VI and VII in patients with infantile autism: Identification of hypoplastic and hyperplastic subgroups with MR imaging American Journal of Roentgenology 162 123–130

    Google Scholar 

  • B. Eggas E. Courchesne O. Saitoh (1995) ArticleTitleReduced size of corpus callosum in autism Archives of Neurology 52 754–801

    Google Scholar 

  • E. Fommbonne C. du Mazaubrun C. Cans H. Granjean (1997) ArticleTitleAutism and associated medical disorders in a French epidemiological survey Journal of the American Academy of Child and Adolescent Psychiatry 36 1561–1569

    Google Scholar 

  • C. Gillberg M. Coleman (1992) The biology of autistic syndromes EditionNumber2 Mac Keith Press London

    Google Scholar 

  • A.L. Hardan N.J. Minshew M.S. Keshavan (2000) ArticleTitleCorpus callosum size in autism Neurology 55 1033–1036

    Google Scholar 

  • International Molecular Genetic Study of Autism Consortium (IMGSAC). (2001). A genomewide screen for autism: Strong evidence for linkage to chromosomes 2q, 7q, and 16p. American Journal of Human Genetics, 69, 570–581.

    Google Scholar 

  • R. Koenig A. Bach U. Woelki K.-H Grzeschik S. Fuchs (2002) ArticleTitleSpectrum of the acrocallosal syndrome American Journal of Medical Genetics 108 7–11

    Google Scholar 

  • Liu, J., Nyholt, D. R., Magnussen, P., Parano, E., Pavone, P., Geschwind, D., Lord, C., Iversen, P., Hoh, J., The Autism Genetic Resource Exchange Consortium, Ott, J., & Gilliam, C. (2001). A Genomewide Screen for Autism susceptibility Loci. American Journal of Human Genetics, 69, 327–340.

    Google Scholar 

  • O.H. Skjeldal E. Sponheim T. Ganes E. Jellum S. Bakke (1998) ArticleTitleChildhood autism: The need for physical investigations Brain Development 20 227–233

    Google Scholar 

  • C.E. Steiner M. M. Guerreiro A. P. Marques-de-Faria (2000) ArticleTitleDifferential diagnosis of autism: The importance of medical evaluation to the genetic counseling The NADD Bulletin 3 48–53

    Google Scholar 

  • J.J. Volpe (1995) Neurobiology of the newborn EditionNumber3 W.B. Saunders Philadelphia 78

    Google Scholar 

Download references

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Correspondence to Antonia Paula marques-de-faria.

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Eduardo steiner, C., Mantovani guerreiro, M. & Paula marques-de-faria, A. Brief Report: Acrocallosal Syndrome and Autism. J Autism Dev Disord 34, 723–726 (2004). https://doi.org/10.1007/s10803-004-5292-0

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  • DOI: https://doi.org/10.1007/s10803-004-5292-0

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