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Journal of Abnormal Child Psychology

, Volume 45, Issue 5, pp 911–920 | Cite as

Acute Stimulant Treatment and Reinforcement Increase the Speed of Information Accumulation in Children with ADHD

  • Whitney D. Fosco
  • Corey N. White
  • Larry W. HawkJr
Article

Abstract

The current studies utilized drift diffusion modeling (DDM) to examine how reinforcement and stimulant medication affect cognitive task performance in children with ADHD. In Study 1, children with (n = 25; 88 % male) and without ADHD (n = 33; 82 % male) completed a 2-choice discrimination task at baseline (100 trials) and again a week later under alternating reinforcement and no-reinforcement contingencies (400 trials total). In Study 2, participants with ADHD (n = 29; 72 % male) completed a double-blind, placebo-controlled trial of 0.3 and 0.6 mg/kg methylphenidate and completed the same task utilized in Study 1 at baseline (100 trials). Children with ADHD accumulated information at a much slower rate than controls, as evidenced by a lower drift rate. Groups were similar in nondecision time and boundary separation. Both reinforcement and stimulant medication markedly improved drift rate in children with ADHD (ds = 0.70 and 0.95 for reinforcement and methylphenidate, respectively); both treatments also reduced boundary separation (ds = 0.70 and 0.39). Reinforcement, which emphasized speeded accuracy, reduced nondecision time (d = 0.37), whereas stimulant medication increased nondecision time (d = 0.38). These studies provide initial evidence that frontline treatments for ADHD primarily impact cognitive performance in youth with ADHD by improving the speed/efficiency of information accumulation. Treatment effects on other DDM parameters may vary between treatments or interact with task parameters (number of trials, task difficulty). DDM, in conjunction with other approaches, may be helpful in clarifying the specific cognitive processes that are disrupted in ADHD, as well as the basic mechanisms that underlie the efficacy of ADHD treatments.

Keywords

ADHD Drift rate Diffusion model Reinforcement Methylphenidate 

Notes

Acknowledgments

This research was funded by grant R01MH069434 to LWH from the National Institute of Mental Health.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in this study.

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Whitney D. Fosco
    • 1
  • Corey N. White
    • 3
  • Larry W. HawkJr
    • 1
    • 2
  1. 1.Department of PsychologyUniversity at Buffalo, SUNYBuffaloUSA
  2. 2.Center for Children and FamiliesUniversity at Buffalo, SUNYBuffaloUSA
  3. 3.Department of PsychologySyracuse UniversitySyracuseUSA

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