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Alternative Factor Models and Heritability of the Short Leyton Obsessional Inventory—Children’s Version

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Abstract

An alternative models framework was used to test three confirmatory factor analytic models for the Short Leyton Obsessional Inventory-Children’s Version (Short LOI-CV) in a general population sample of 517 young adolescent twins (11–16 years). A one-factor model as implicit in current classification systems of Obsessive–Compulsive Disorder (OCD), a two-factor obsessions and compulsions model, and a multidimensional model corresponding to the three proposed subscales of the Short LOI-CV (labelled Obsessions/Incompleteness, Numbers/Luck and Cleanliness) were considered. The three-factor model was the only model to provide an adequate explanation of the data. Twin analyses suggested significant quantitative sex differences in heritability for both the Obsessions/Incompleteness and Numbers/Luck dimensions with these being significantly heritable in males only (heritability of 60% and 65% respectively). The correlation between the additive genetic effects for these two dimensions in males was 0.95 suggesting they largely share the same genetic risk factors.

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Acknowledgment

The authors would like to thank those who participated in the study and staff of the Eastern, Western and Southern Health and Social Services Boards, Homefirst Community Trust and the Causeway Health and Social Services Trust who facilitated access to the Child Health System Database.

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Moore, J., Smith, G.W., Shevlin, M. et al. Alternative Factor Models and Heritability of the Short Leyton Obsessional Inventory—Children’s Version. J Abnorm Child Psychol 38, 921–934 (2010). https://doi.org/10.1007/s10802-010-9414-1

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