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Catalyst-free α-bromination of acetophenones by two-phase electrolysis

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Abstract

A convenient and catalyst-free method for the α-bromination of acetophenones using NaBr and CHCl3 in biphasic electrolysis with H2SO4 as a supporting electrolyte at room temperature has been introduced. This approach results in an excellent yield of α-bromo acetophenones with high selectivity in a beaker-type cell equipped with C/SS electrodes. To achieve good yield with high current efficiency, various optimization studies are carried out and reported.

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Authors and Affiliations

  1. Department of Chemistry, Periyar University, Salem, Tamil Nadu, 636001, India

    V. Sathya & D. Gopi

  2. Department of Chemistry, Namakkal Kavignar Ramalingam Government Arts College for Women, Namakkal, Tamil Nadu, 637001, India

    V. Sathya

  3. Department of Chemistry, Vivekanandha College of Arts and Sciences for Women (Autonomous), Tiruchengode, Namakkal, Tamil Nadu, 637205, India

    R. Jagatheesan & V. Jeevanantham

  4. Department of Biochemistry, Vivekanandha College of Arts and Sciences for Women (Autonomous), Tiruchengode, Namakkal, Tamil Nadu, 637205, India

    P. Baby Shakila

Authors
  1. V. Sathya
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  2. R. Jagatheesan
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  3. V. Jeevanantham
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  4. D. Gopi
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  5. P. Baby Shakila
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Contributions

A.B. and B.C. conceived of the presented idea. A.B. developed the theory and performed the computations. C.D. and D.E. verified the analytical methods. B.C. encouraged A.B. to investigate and supervised the findings of this work. All authors discussed the results and contributed to the final manuscript.

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Correspondence to D. Gopi.

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Sathya, V., Jagatheesan, R., Jeevanantham, V. et al. Catalyst-free α-bromination of acetophenones by two-phase electrolysis. J Appl Electrochem 53, 1887–1894 (2023). https://doi.org/10.1007/s10800-023-01890-3

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