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Success rate in micropulse diode laser treatment with regard to lens status, refractive errors, and glaucoma subtypes

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Abstract

Purpose

To evaluate the efficacy of micropulse transscleral cyclophotocoagulation (MP-TSCPC) considering different characteristics: glaucoma subtypes and lens status.

Methods

A retrospective case-series study was designed to evaluate intraocular pressure (IOP), and the number of IOP-lowering medications, used by glaucoma patients treated with MP-TSCPC between 2016 and 2019. Cases had a follow-up period of 12 months. Achieving an IOP reduction higher than 20%, or the decrease of at least one IOP-lowering medication, was considered a successful outcome. The same population was analyzed by classifying them in two groups as: glaucoma subtypes and lens status. The baseline spherical equivalent (SE) was also calculated for considering association with the achieved IOP.

Results

A total of 86 eyes were included. In most cases, IOP and IOP-lowering medications were decreased with a statistically significant difference (p < 0.0001), and all of them had a successful outcome. The percentage of IOP drop oscillated between 25.9% (open-angle glaucoma sub-group) and 37.5% (pseudoexfoliative glaucoma sub-group), 12 months after surgery. The difference between the groups was not statistically significant (p 0.20 and 0.32 for glaucoma subtypes and lens status, respectively). The Pearson’s coefficient obtained was low for the SE and IOP association, at the 12 -month postoperative mark (− 0.009; p < 0.001).

Conclusions

The MP-TSCPC treatment was successful in decreasing IOP and IOP-lowering medications, in different glaucoma subtypes. Differences between groups (glaucoma subtypes, phakic and pseudophakic eyes) were not statistically significant. No association was found between the SE and the IOP achieved value after MS-TSCPC treatment.

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Data availability

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Code availability

XLMiner Analysis Toolpak Frontline Systems Inc. was used. It is a free software to perform statistical analysis in Google Sheets.

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Acknowledgments

The authors would like to acknowledge Rodrigo M. Torres M.D. Ph.D. for his scientific advice.

Funding

None; this research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

  1. Centro de Ojos Quilmes, Humberto Primo, 298, Quilmes, Buenos Aires, Argentina

    Virginia Zanutigh, Luciano Daniel Perrone, Gastón Gómez-Caride, Franco Perrone, Gerardo Valvecchia & Celina Logioco

Authors
  1. Virginia Zanutigh
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  2. Luciano Daniel Perrone
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  3. Gastón Gómez-Caride
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  4. Franco Perrone
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  5. Gerardo Valvecchia
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  6. Celina Logioco
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by VZ, LDP, GGC, FP, GV, and CL. The first draft of the manuscript was written by VZ and CL, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Virginia Zanutigh.

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Conflict of interests

The authors declare that they have no competing interests.

Ethical approval

The study was conducted following the Helsinki tenets in a private clinic in Buenos Aires (Centro de Ojos Quilmes), Argentina, after the Institutional Review Board approved the study protocol.

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Zanutigh, V., Perrone, L.D., Gómez-Caride, G. et al. Success rate in micropulse diode laser treatment with regard to lens status, refractive errors, and glaucoma subtypes. Int Ophthalmol 43, 2407–2417 (2023). https://doi.org/10.1007/s10792-023-02640-2

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  • DOI: https://doi.org/10.1007/s10792-023-02640-2

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