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Evaluation of VEP parameters in patients before and after cardiopulmonary by-pass surgery

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Abstract

Purpose

Coronary bypass surgery is emphasized in aetiology of ischemic optic neuropathy. Our aim in this study was to investigate the pattern visual evoked potentials (PVEP) in patients before and after coronary bypass surgery.

Methods

Thirty-one patients were included in the study. After a full ophthalmological evaluation, PVEP was assesed in the pre and postoperative periods. Operative times, hematological parameters, blood pressures, number of transfusions, body temperatures, anaesthetic drugs and systemic illnesses were recorded for each patient.

Results

The mean age of the patients were 59 ± 10.4 years. There was 22 men and 9 women in the study. Only 3 of them needed transfusion during the surgery. The mean duration of the surgery was 3.2 ± 0.7 h. None of the patients had a history of visual disturbance or postoperative ischemic optic neuropathy. The mean VEP P100 amplitude was not statistically significantly different but the mean VEP P100 latency showed statistically significant difference between the preoperative and postoperative periods. (p = 0.014) This significance was more appereant in patients with systemic illnesses. (p = 0.023) There was a positive correlation between the age and VEP P100 latency (r = 0.402, p < 0.05).

Conclusions

Although surgical techniques and equipments are developing each day in the field of cardiopulmonary bypass surgery, the contributing factors such as hypothermia, anemia and diabetes still seem to affect neurophysiological functions even after a noncomplicated surgery.

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Authors and Affiliations

  1. School of Medicine, Department of Ophthalmology, Gaziosmanpaşa University, Tokat, Turkey

    Alper Güneş, Şerife Gülhan Konuk & Helin Deniz Demir

  2. School of Medicine, Department of Neurology, Gaziosmanpaşa University, Tokat, Turkey

    Semiha Kurt

  3. Park Hayat Hospital, Afyon, Turkey

    Erdinç Naseri

  4. School of Medicine, Department of Biostatistics, Sakarya University, Sakarya, Turkey

    Ünal Erkorkmaz

Authors
  1. Alper Güneş
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  2. Şerife Gülhan Konuk
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  3. Helin Deniz Demir
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  4. Semiha Kurt
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  5. Erdinç Naseri
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  6. Ünal Erkorkmaz
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Correspondence to Alper Güneş.

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All participants agreed to the collection and anonymous publication of the data.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the Tokat Gaziosmanpaşa University Faculty of Medicine clinical research ethics committee (20-KAEK-23) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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The Clinical Research Registration number obtained from the clinical research ethics committee of Tokat Gaziosmanpaşa University Faculty of Medicine is 20-KAEK-235.

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Güneş, A., Konuk, Ş.G., Demir, H.D. et al. Evaluation of VEP parameters in patients before and after cardiopulmonary by-pass surgery. Int Ophthalmol 43, 397–402 (2023). https://doi.org/10.1007/s10792-022-02435-x

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  • DOI: https://doi.org/10.1007/s10792-022-02435-x

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