Abstract
Aim
To assess the repeatability of a new optical biometer (OA-2000, Tomey, Japan) based on swept-source optical coherence tomography (SS-OCT) and Placido-disk topography in dry eyes with cataracts.
Method
A cross-sectional study was performed. Two hundred sixteen eyes of 216 cataract patients were enrolled in our hospital from March 2020 to December 2020. According to the subjective symptoms and objective examination of dry eye, the patients were assigned to dry eye group and non-dry eye group. Axial length (AL), keratometry readings (K), lens thickness (LT), anterior chamber depth (ACD), central corneal thickness (CCT) and white-to-white (WTW) distance were measured by one skilled operator. The repeatability of each parameter based on within-subject standard deviation (Sw), repeatability limit of standard deviation (2.77Sw), coefficient of variation (CoV) and intra-class correlation coefficient (ICC) was evaluated.
Result
There was no significant difference in age and gender between the two groups. NiaBUT and NifBUT in the dry eye group were significantly lower than those in the non-dry eye group (p < 0.05). The ICC mean values of AL, K1, K2, Km, ACD, LT and CCT were all greater than 0.960, except WTW. In the dry eye group, except CCT and WTW, the Sw scores for other biometric parameters were lower than 0.201, 2.77Sw scores were lower than 0.557, CoV(%) was less than 1%, and ICC mean values were greater than 0.964. Among them, the Sw scores for AL, LT and ACD were lower than 0.035, the 2.77Sw scores were lower than 0.097, and the ICC mean values are greater than 0.990.
Conclusion
The ocular biological parameters measured by SS-OCT have good repeatability for age-related cataract patients with dry eyes, in which the AL, LT and ACD are the highest repeatable. However, more attention should be paid for WTW in clinical application since repeatability influence.
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Data availability
All data generated or analyzed during this study are included in this published article.
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YF was involved in conception and design of the work and drafting the manuscriptYF CY, YL, JZJ and LJW contributed to data collection YF and WY were involved in supervision and statistical analysis YF, CY, YL, JZJ and LJW contributed to analysis and interpretation of the data; and All authors were involved in critical revision of the manuscript and approval of the final manuscript.
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Yang, F., Chang, Y., Yang, L. et al. Evaluation of the repeatability of optical coherence tomography in patients with age-related cataract associated with dry eye. Int Ophthalmol 43, 233–238 (2023). https://doi.org/10.1007/s10792-022-02421-3
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DOI: https://doi.org/10.1007/s10792-022-02421-3