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Mapping research trends of chronic ocular graft-versus-host disease from 2009 to 2020: a bibliometric analysis

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Abstract

Purpose

To evaluate the global scientific output of research on ocular chronic Graft versus host disease (cGVHD) and explore the current status and trends in this field over the past decade by bibliometric analysis.

Methods

The bibliometric search was performed in the Web of Science Core Collection (WoSCC) database. VOSviewer v.1.6.16 was used to map the knowledge domain. The annual number of publications and citations, distribution of countries and organizations, productivity of authors and journals, international collaborations, cited references, and keywords in the field of ocular cGVHD were visualized.

Results

In total, 398 peer-reviewed publications from 2009 to 2020 on ocular cGVHD were retrieved. The United States among all countries had the highest number of publications and citations, and Keio University was the most effective institution. Dana, R ranks the highest regarding the number of publications and citations on ocular cGVHD. Cornea and Biology of Blood and Marrow Transplantation were the most-cited journals in ocular cGVHD studies from ophthalmology and hematology, respectively. The top-cited references were primarily centered on dry eye. The keywords constituted three clusters: (1) consensus criteria and epidemiology of ocular cGVHD, (2) preclinical medical research of ocular cGVHD, and (3) treatment.

Conclusion

Based on the data retrieved from WoSCC, a comparative analysis of the quantity and quality of papers on ocular cGVHD was conducted through bibliometric methods. This may contribute to better understanding of the status of ocular cGVHD study. The three major research topics shed new light on the ocular cGVHD study as well as meaningful materials for scholars to identify potential collaborators and promising partner institutions.

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Acknowledgements

The authors thank all reviewers for their valuable comments and support.

Funding

This study was funded by Higher Education Institutions Scientific Research Project of Liaoning Province (Grant No. LJKZ0773) and Medical Science and Technology Project of Zhejiang Province (Grant No. 2021KY157).

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Author notes

  1. Jiawei Xu and Fangkun Zhao have contributed equally to this work and share first authorship.

Authors and Affiliations

  1. Department of Ophthalmology, The First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou, 310003, China

    Jiawei Xu, Jianxia Fang, Meipan Shi, Junchao Pan, Wen Sun & Chixin Du

  2. Department of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Shenyang, Liaoning, China

    Fangkun Zhao

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  1. Jiawei Xu
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Correspondence to Chixin Du.

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Xu, J., Zhao, F., Fang, J. et al. Mapping research trends of chronic ocular graft-versus-host disease from 2009 to 2020: a bibliometric analysis. Int Ophthalmol 42, 3963–3976 (2022). https://doi.org/10.1007/s10792-022-02380-9

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  • DOI: https://doi.org/10.1007/s10792-022-02380-9

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