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Five-year clinical outcomes of rigid iris-fixated phakic intraocular lens in northern Chinese

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Abstract

Purpose

To investigate the 5-year clinic outcomes of rigid iris-fixated pIOL on the visual performance, complications and intraocular light scattering in northern Chinese.

Methods

Thirty eyes implanted with iris-fixated phakic IOLs (pIOLs group) and 34 eyes with high myopia (myopia group) were involved in this study. At preoperatively, 6 months, 1, 3, and 5 years postoperatively, the uncorrected visual acuity (UCVA), best-spectacle corrected visual acuity (BSCVA), endothelial cell density (ECD), and intraocular pressure (IOP) were measured in pIOLs group. The objective scatter index (OSI), modulation transfer function cut off (MTF cut off), and Strehl ratio were measured by Optical Quality Analysis System and a pseudophakic dysphotopsia questionnaire (PDQ) was used to evaluate the subjects’ satisfaction in pIOLs and myopia groups.

Results

At 5 years postoperatively, an UCVA of 20/20 or better was found in 43.33% of eyes in pIOLs group. At 6 months, 1, 3, and 5 years postoperatively, the mean ECD decrease were 1.29% ± 0.45%, 2.59% ± 1.30%, 6.67% ± 2.26%, and 10.80% ± 3.48%. The value of OSI in pIOLs group was significantly higher than that in myopia group (P < 0.001). The PDQ results showed that the subjects in myopia group complained less with intolerance of bright lights than those in pIOLs group. The values of Strehl ratio and MTF cut off in pIOLs group were significantly lower than that in myopia group (P < 0.001).

Conclusions

Iris-fixated pIOL induce more intraocular light scattering. A significant decrease in ECD was observed at 5 years postoperatively. An annual evaluation of ECD is necessary for patients undergoing pIOL implantation.

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Data availability

All data and materials during the present study are available from the corresponding author.

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Acknowledgements

The authors thank Dr. Olson R.J. for the permission to use pseudophakic dysphotopsia questionnaire in this study.

Funding

The study was supported by Tianjin health science and technology Project (ZC20189), Tianjin eye hospital science and technology foundation (YKYB2002), and Tianjin Key Medical Discipline (Specialty) Construction Project.

Author information

Author notes

  1. Jun Li and Lin-Lin Song contributed equally to this study and should be considered co-first authors.

Authors and Affiliations

  1. Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin Eye Hospital, Nankai University Affiliated Eye Hospital, Clinical College of Ophthalmology Tianjin Medical University, No. 4 Gansu Road, Heping District, Tianjin, 300020, China

    Jun Li & Hui Song

  2. Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, 300384, China

    Lin-Lin Song

Authors
  1. Jun Li
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  3. Hui Song
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Contributions

JL and HS contributed to the study design, data analysis and data interpretation. JL and LLS contributed to collecting the data, data interpretation and preparing the manuscript. Jun Li and Lin-lin Song should be considered co-first authors. All authors read and approved the final version of the manuscript.

Corresponding authors

Correspondence to Jun Li or Hui Song.

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Conflict of interest

Authors declare that they have no competing interests.

Ethical approval

All procedure was in accordance with the Declaration of Helsinki and approved by Tianjin eye hospital ethics committee.

Informed consent

Informed consent was obtained from all participants included in the study.

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We confirm that this manuscript has not been published elsewhere and is not under consideration by another journal. All authors have approved the manuscript and agree with submission to International Ophthalmology. The authors declare that there is no conflict of interest. This paper has not been published elsewhere and not currently under consideration by any other publisher.

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Li, J., Song, LL. & Song, H. Five-year clinical outcomes of rigid iris-fixated phakic intraocular lens in northern Chinese. Int Ophthalmol 42, 2551–2561 (2022). https://doi.org/10.1007/s10792-022-02303-8

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  • DOI: https://doi.org/10.1007/s10792-022-02303-8

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