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Optic coherence tomography angiography findings in fuchs heterochromic iridocyclitis

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Abstract

Purpose

To evaluate macular capillary perfusion in patients with fuchs heterochromic iridocyclitis (FHI) by using optical coherence tomography angiography (OCTA).

Material and Method

A total of 19 eyes of 19 patients with unilateral FHI underwent detailed eye examination. OCTA (RTVue-XR Avanti) images were obtained from both eyes. OCTA parameters, including foveal avascular zone, superficial capillary plexus and deep capillary plexus vessel densities, were compared between the involved and fellow control eyes.

Results

The median age of the patients (11 females, 8 males) was 42.0 ± 9.63 (range 24–57) years. DCP and SCP densities at the parafoveal and perifoveal area were significantly lower in the FHI eyes compared to the control eyes (44.80 ± 5.24% vs. 54.70 ± 3.76% and 43.30 ± 5.10% vs. 53.70 ± 2.73%, respectively; p < 0.05). The median FAZ was 0.29 ± 0.12 (0.11–0.42) mm2 in the FHI eyes and 0.26 ± 0.09 (0.10–0.40) mm2 in the control eyes. This difference did not reach statistical significance (p = 0.199).

Conclusion

Macular capillary perfusion was significantly reduced in both SCP and DCP in the eyes with FHI. FHI, which is known to affect the choroid layer, could also compromise macular capillary perfusion of the retina.

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The author(s) received no financial support for the research, authorship, and/or publication of this article.

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Authors and Affiliations

  1. Department of Ophthalmology, Ege University School of Medicine, 3rd floor, Eye Clinic, Bornova, Izmir, 35100, Turkey

    Cumali Degirmenci, Semir Yarimada, Suzan Guven Yilmaz, Serhad Nalcaci, Halil Ates & Filiz Afrashi

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  1. Cumali Degirmenci
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  2. Semir Yarimada
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Correspondence to Cumali Degirmenci.

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Degirmenci, C., Yarimada, S., Guven Yilmaz, S. et al. Optic coherence tomography angiography findings in fuchs heterochromic iridocyclitis. Int Ophthalmol 42, 2519–2524 (2022). https://doi.org/10.1007/s10792-022-02299-1

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  • DOI: https://doi.org/10.1007/s10792-022-02299-1

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