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Common ocular findings in patients with acne rosacea

Abstract

Purpose

To evaluate ocular surface manifestations in patients with acne rosecea (AR) and to find out main features indicating a propensity toward an association with disease diagnosis.

Methods

Right eyes of consecutive 76 AR patients and 113 age-gender matched healthy subjects were enrolled. Ophthalmologic examinations including tear break-up time (t-BUT) and Schirmer-2 tests to analyze tear film insufficiency, optical coherence tomography (OCT)-assisted infrared meibography to analyze meibomian gland drop-out, and Ocular Surface Disease Index (OSDI) questionnaire were performed in all participants.

Results

No statistically differences were found in visual acuity, intraocular pressure, central corneal thickness, and axial length assessments between the study and control eyes. Study eyes had more foreign body sensation, itching, dryness, hyperemia, conjunctival telangiectasia, and meibomitis (p ≤ 0.005, for all). Significantly higher t-BUT and Schirmer-2 tests; lower-eyelid and total OCT meibography; and OSDI scores were found in AR patients (p < 0.05, for all). Among all, only conjunctival telangiectasia (p = 0.001; OR:0.070, 95% CI:0.015–0.330) was found to be major independent predictor for AR diagnosis.

Conclusion

Detailed slit-lamp examination to detect any conjunctival telangiectasia seems to be crucial in recalcitrant dry eye cases, not to miss underlying AR. Especially, lower-eyelid OCT meibography score may be sensitively used for disease staging.

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Authors and Affiliations

Authors

Contributions

All co authors have all participated sufficiently in the conception and design of this work and interpretation of the data as well as in the writing of the manuscript.

Corresponding author

Correspondence to Taylan Ozturk.

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Conflict of Interest

The authors declared that there is no conflict of interest.

Data availability

Available upon request after fogging the names of the participants.

Code availability

The data were stored on a computerized database and analyzed using SPSS version 22.0 statistical software (IBM, Armonk, NY).

Ethical approval

Approval was obtained from the ethics committee of Dokuz Eylul University. The procedures used in this study adhere to the tenets of the Declaration of Helsinki.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Patients signed informed consent regarding publishing their data and photographs.

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Ozturk, T., Kayabasi, M., Ozbagcivan, O. et al. Common ocular findings in patients with acne rosacea. Int Ophthalmol 42, 1077–1084 (2022). https://doi.org/10.1007/s10792-021-02093-5

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  • DOI: https://doi.org/10.1007/s10792-021-02093-5

Keywords

  • Acne rosacea
  • Dry eye
  • Infrared meibography
  • Meibomian gland dysfunction