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Wave front aberrations induced from biomechanical effects after customized myopic laser refractive surgery in finite element model

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Abstract

Purpose

A customized myopic refractive surgery was simulated by establishing a finite element model of the human eye, after which we studied the wave front aberrations induced by biomechanical effects and ablation profile after wave front-guided LASIK surgery.

Methods

Thirty myopia patients (i.e., 60 eyes) without other eye diseases were selected. Their ages, preoperative spherical equivalent, astigmatism, and wave front aberration were then obtained, in addition to the mean spherical equivalent error range − 4 to − 8D. Afterward, wave front-guided customized LASIK surgery was simulated by establishing a finite element eye model, followed by the analysis of the wave front aberrations induced by the surface displacement from corneal biomechanical effects, as well as customized ablation profile. Finally, the preoperative and induced aberrations were statistically analyzed.

Results

Comatic aberrations were the main wave front abnormality induced by biomechanical effects, and the wave front aberrations induced by the ablation profile mainly included coma and secondary coma, as well as sphere and secondary-sphere aberrations. Overall, the total high-order aberrations (tHOAs), total coma (C31), and sphere (\(C_{4}^{0}\)) increased after wave front-guided customized LASIK surgery. According to our correlation analyses, coma, sphere, and tHOAs were significantly correlated with decentration. Additionally, the material parameters of ocular tissue were found to affect the postoperative wave front aberrations. When the material parameters of the sclera remained constant but those of cornea increased, the induced wave front aberrations were reduced.

Conclusion

All biomechanical effects of cornea and ablation profile had significant effects on postoperative wave front aberrations after customized LASIK refractive surgery; however, the effects of the ablation profile were more notorious. Additionally, the characteristics of biomechanical materials have influence on the clinical correction effect.

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Data availability

Data are transparent.

Code and/or material availability

In the process of research, we use MATLAB, ANSYS and NX and have program.

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Acknowledgements

Thank you to everyone who has helped this study.

Funding

Supported by the Natural National Science Foundation of China (NSFC) (61465010 and 81873684), the National Key Research and Development Program of China (2018YFE0115700) and Jiangxi Nature Science Foundation (20192BAB207035).

Author information

Authors and Affiliations

  1. Nanchang Hangkong University, Nanchang, 330063, China

    Ruirui Du, Weijian Peng, Ruizhi Yang, Shifeng Nie, Huirong Xiao, Jiahui Gong, Yu Dai & Jiahao Deng

  2. Key Laboratory of Nondestructive Test (Ministry of Education), Nanchang Hangkong University, Nanchang, 86-18170938193, 330063, China

    Lihua Fang

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  1. Ruirui Du
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  2. Lihua Fang
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Contributions

DR contributed to conceptualization, methodology, software, formal analysis, writing—original draft, data curation, supervision. FL contributed to conceptualization, visualization, resources, writing—review and editing, funding acquisition, project administration, project administration. PW contributed to conceptualization, data curation, validation. YR contributed to software, visualization. NS contributed to software, methodology. XH contributed to project administration. GJ contributed to software, formal analysis. DY contributed to software, data curation. Deng Jiahao contributed to software, data curation.

Corresponding author

Correspondence to Lihua Fang.

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Conflict of interest

The authors have no relevant financial or non-financial interests to disclose.

Research involving human participants

Our research involving human participants and no animals.

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Informed consent was obtained from all individual participants included in the study.

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Approval was obtained from the ethics committee of Tianjin Eye Hospital.

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This study does not involve the animal.

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Informed consent was obtained from all individual participants included in the study.

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Du, R., Fang, L., Peng, W. et al. Wave front aberrations induced from biomechanical effects after customized myopic laser refractive surgery in finite element model. Int Ophthalmol 42, 81–94 (2022). https://doi.org/10.1007/s10792-021-02003-9

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  • DOI: https://doi.org/10.1007/s10792-021-02003-9

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