Skip to main content

Advertisement

Log in

Role of multicolour imaging in post-fever retinitis involving posterior pole

  • Original Paper
  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To describe composite multicolour (MC) imaging features along with the monocoloured fundus reflectance images in active and resolving stages of post-fever retinitis (PFR).

Methods

Retrospective image analysis of cases of PFR who underwent dilated retinal clinical examination followed by optical coherence tomography and MC imaging.

Results

Twenty-five eyes of 18 patients diagnosed with PFR were included. There were 11 males and 7 females. Mean age of patients was 30.63 years. The retinitis lesion appeared bright white on MC image and white mainly on blue and green reflectance images during the active stages of PFR. The lesion appeared dull-grey to greyish white during the resolving stages and as dull-green in resolved cases. The active stages showed the presence of intraretinal/subretinal fluid which appeared as green colour on MC images and less green to normal during resolving stages. Hard exudates were seen as bright yellow- or orange-coloured spots on MC image during the resolving stages of the disease.

Conclusion

The different stages of PFR show different colour on multicolour image and different reflectance patterns on individual colour reflectance channels. Hence, multimodal fundus imaging with different wavelength can be helpful for differentiation of activity in PFR.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

Data availability

The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.

References

  1. Bansal R, Gupta V, Gupta A (2010) Current approach in the diagnosis and management of panuveitis. Indian J Ophthalmol 58:45–54. https://doi.org/10.4103/0301-4738.58471

    Article  PubMed  PubMed Central  Google Scholar 

  2. Sudharshan S, Ganesh SK, Biswas J (2010) Current approach in the diagnosis and management of posterior uveitis. Indian J Ophthalmol 58:29–43. https://doi.org/10.4103/0301-4738.58470

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Gupta N, Tripathy K Retinitis. [Updated 2020 Aug 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK560520/

  4. Kawali A, Mahendradas P, Mohan A et al (2019) Epidemic retinitis. Ocul Immunol Inflamm 27:571–577. https://doi.org/10.1080/09273948.2017.1421670

    Article  PubMed  Google Scholar 

  5. Chawla R, Tripathy K, Temkar S et al (2018) An imaging-based treatment algorithm for posterior focal retinitis. Ophthalmol Eye Dis 10:251584141877442. https://doi.org/10.1177/2515841418774423

    Article  Google Scholar 

  6. Hazirolan D, Sungur G, Demir N et al (2010) Focal posterior pole viral retinitis. Eur J Ophthalmol 20:925–930. https://doi.org/10.1177/112067211002000518

    Article  PubMed  Google Scholar 

  7. Khairallah M, Chee SP, Rathinam SR et al (2010) Novel infectious agents causing uveitis. Int Ophthalmol 30:465–483. https://doi.org/10.1007/s10792-009-9319-6

    Article  PubMed  Google Scholar 

  8. Vishwanath S, Badami K, Sriprakash KS et al (2014) Post-fever retinitis: a single center experience from south India. Int Ophthalmol 34:851–857. https://doi.org/10.1007/s10792-013-9891-7

    Article  PubMed  Google Scholar 

  9. Mahendradas P, Kawali A, Luthra S et al (2020) Post-fever retinitis—Newer concepts. Indian J Ophthalmol 68:1775–1786. https://doi.org/10.4103/ijo.IJO_1352_20

    Article  PubMed  PubMed Central  Google Scholar 

  10. Srinivasan S, Agarwal S, Mahendradas P et al (2020) Post fever uveoretinal manifestations in an immunocompetent individual. EMJ Allergy Immunol 5:91–105

    Google Scholar 

  11. Khochtali S, Gargouri S, Zina S et al (2018) Acute multifocal retinitis: a retrospective review of 35 cases. J Ophthal Inflamm Infect 8:18. https://doi.org/10.1186/s12348-018-0160-9

    Article  CAS  Google Scholar 

  12. Gupta MP, Patel S, Orlin A et al (2018) Spectral domain optical coherence tomography findings in macula-involving cytomegalovirus retinitis. Retina 38:1000–1010. https://doi.org/10.1097/IAE.0000000000001644

    Article  PubMed  Google Scholar 

  13. Tan ACS, Fleckenstein M, Schmitz-Valckenberg S, Holz FG (2016) Clinical application of multicolor imaging technology. Ophthalmologica 236:8–18. https://doi.org/10.1159/000446857

    Article  PubMed  Google Scholar 

  14. Feng HL, Sharma S, Stinnett S et al (2019) Identification of posterior segment pathology with en face retinal imaging using multicolor confocal scanning laser ophthalmoscopy. Retina (Philadelphia, Pa) 39:972–979. https://doi.org/10.1097/IAE.0000000000002111

    Article  Google Scholar 

  15. Venkatesh R, Bavaharan B, Yadav NK et al (2018) Multicolor imaging in choroidal osteomas. Int J Retina Vitreous 4:46. https://doi.org/10.1186/s40942-018-0150-y

    Article  PubMed  PubMed Central  Google Scholar 

  16. Manivannan A, Van der Hoek J, Vieira P et al (2001) Clinical investigation of a true color scanning laser ophthalmoscope. Arch Ophthalmol 119:819–824

    Article  CAS  PubMed  Google Scholar 

  17. Keane PA, Sadda SR (2014) Retinal imaging in the twenty-first century: state of the art and future directions. Ophthalmology 121:2489–2500. https://doi.org/10.1016/j.ophtha.2014.07.054

    Article  PubMed  Google Scholar 

  18. Elsner AE, Burns SA, Weiter JJ, Delori FC (1996) Infrared imaging of sub-retinal structures in the human ocular fundus. Vision Res 36:191–205. https://doi.org/10.1016/0042-6989(95)00100-E

    Article  CAS  PubMed  Google Scholar 

  19. Muftuoglu IK, Gaber R, Bartsch D-U et al (2018) Comparison of conventional color fundus photography and multicolor imaging in choroidal or retinal lesions. Graefes Arch Clin Exp Ophthalmol 256:643–649. https://doi.org/10.1007/s00417-017-3884-6

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

We would like to thank our technicians, Mr Abhishek, Mr Deekshit, Mr Manjunath and Mr Madhu, for their contribution in acquiring the images and providing them to us for analysis in this study.

Funding

No funding has been obtained for this research work.

Author information

Authors and Affiliations

Authors

Contributions

RV helped in conceptualizing the study, analysing the data, interpreting the findings, writing & reviewing the manuscript. SS, MPA, AK contributed to clinical management of the patient. NKY and RS reviewed the manuscript and NR and RAM acquired the data.

Corresponding author

Correspondence to Ramesh Venkatesh.

Ethics declarations

Conflict of interest

None of the authors have any conflict of interest to declare.

Animal research

This article does not contain any studies with animals performed by any of the authors.

Ethical approval and consent to participate

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee (Narayana Nethralaya Institutional Review Board—C/2018/02/03) and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Consent for publication

Informed consent was obtained from all individual participants included in the study. The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given his consent for his/her images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sanjay, S., Reddy, N.G., Kawali, A. et al. Role of multicolour imaging in post-fever retinitis involving posterior pole. Int Ophthalmol 41, 3797–3804 (2021). https://doi.org/10.1007/s10792-021-01951-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10792-021-01951-6

Keywords

Navigation