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Long-term outcomes of initial trabeculectomy in glaucoma associated with granulomatous and non-granulomatous uveitis

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Abstract

Purpose

To evaluate the outcomes of initial trabeculectomy in granulomatous and non-granulomatous uveitis.

Methods

Retrospective comparative study of 68 eyes that underwent an initial trabeculectomy.

Results

The mean follow-up was 74.18 and 74.86 months in both groups (p = 0.95). The intraocular pressure decreased from 40.03 mmHg ( ± 7.2) and 36.48 mmHg ( ± 11.3) to 14.00 mmHg ( ± 6.2) and 13.48 mmHg ( ± 5.7), the number of medications decreased from 3.73 ( ± 0.7) and 3.58 ( ± 0.9) to 1.00 ( ± 1.4) and 1.13 ( ± 1.4) on the last follow-up (p < 0.01) in the granulomatous and non-granulomatous groups, respectively. More eyes in the granulomatous uveitis group developed delayed postoperative complications like cataract, transient hypotony and glaucoma progression. Success rates were 64.9 and 71.0%, while failure rates were 35.1 and 29.0% in both groups (p = 0.84).

Conclusions

Trabeculectomy seems to have comparable IOP control and survival in granulomatous and non-granulomatous uveitis. Nevertheless, more eyes in the granulomatous uveitis group developed late-onset complications.

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Data availability

The authors confirm that the data supporting the findings of this study are available within the article.

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Authors and Affiliations

  1. Department of Ophthalmology, College of Medicine, King Saud University, P.O. Box 245, Riyadh, 11411, Saudi Arabia

    Faisal A. Almobarak

  2. Glaucoma Research Chair, King Saud University, Riyadh, Saudi Arabia

    Faisal A. Almobarak

  3. King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia

    Faisal A. Almobarak, Ali H. Alharbi, Ibrahim Aljadaan & Hassan Aldhibi

  4. King Abdullah Medical City, Makkah, Saudi Arabia

    Ali H. Alharbi

Authors
  1. Faisal A. Almobarak
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  2. Ali H. Alharbi
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  3. Ibrahim Aljadaan
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  4. Hassan Aldhibi
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Correspondence to Faisal A. Almobarak.

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Almobarak, F.A., Alharbi, A.H., Aljadaan, I. et al. Long-term outcomes of initial trabeculectomy in glaucoma associated with granulomatous and non-granulomatous uveitis. Int Ophthalmol 41, 3459–3470 (2021). https://doi.org/10.1007/s10792-021-01910-1

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  • DOI: https://doi.org/10.1007/s10792-021-01910-1

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