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Clinical efficacy of inferior peripheral irido-capsulo-hyaloidotomy for pseudophakic malignant glaucoma

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Abstract

Purpose

The present research aimed to investigate the effects of Inferior peripheral irido-capsulo-hyaloidotomy for the management of pseudophakic malignant glaucoma.

Method

Ten pseudophakic eyes with aqueous misdirection were diagnosed between September 2017 and December 2018 (10 eyes of 8 patients), which were included in the prospective consecutive case series study. Seven eyes underwent Inferior laser peripheral irido-capsulo-hyaloidotomy, and three eyes underwent pars plana vitrectomy, zonulo-capsulo-hyaloidectomy, and inferior iridectomy.

Results

Eight eyes (80%) had angle-closure glaucoma. The mean duration of the follow-up was 12.25 ± 3.05 months (ranging from 10–18 months). The patients had a mean age of 69.25 ± 6 years. The IOP at the onset of malignant glaucoma was found to be 33.8 ± 5.5 mmHg, which was reduced to 13.9 ± 2.7 mmHg at the final visit (P value = 0.002). The reduction in the number ± SD of anti-glaucoma medications (3.3 ± 0.48 to 1.4 ± 0.51) and improvement in mean ± SD LogMAR visual acuity (1.2 ± 0.06 to 0.61 ± 0.26) between the onset and final visit were significant (p = 0.004 and P = 0.005, respectively). All the patients responded to Inferior peripheral irido-capsulo-hyaloidotomy (with YAG laser or with the surgical procedure), which led to a significant reduction in intraocular pressure (IOP) and deepening of the anterior chamber.

Conclusion

The success rate of peripheral irido-capsulo-hyaloidotomy with laser or surgical procedure in the inferior quadrant was high regarding pseudophakic malignant glaucoma patients. The establishment of a patent inferior communication between the vitreous cavity and the anterior chamber was the main component in the treatment of pseudophakic malignant glaucoma patients.

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Data Availability

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Funding

The author(s) received no specific funding for this work. Authors do not have any financial interests in any of the mentioned products.

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Authors and Affiliations

  1. Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University Medical Sciences, Isfahan, Iran

    Afsaneh Naderi Beni, Hamid fesharaki, Heshmatollah Ghanbari & Farzan Kianersi

  2. Department of Laboratory, Shahrekord University of Medical Sciences, Shahrekord, Iran

    Fariba Naderi Beni

  3. Department of Basic Science, Islamic Azad University, Shahrekord Branch, Shahrekord, Iran

    Batool Naderi Beni

  4. Ophthalmology Department, Isfahan Eye Research Center, Feiz Hospital, Modares Street, Isfahan, Iran

    Afsaneh Naderi Beni

Authors
  1. Afsaneh Naderi Beni
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  2. Hamid fesharaki
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  3. Heshmatollah Ghanbari
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  4. Farzan Kianersi
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  5. Fariba Naderi Beni
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  6. Batool Naderi Beni
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Contributions

These authors contributed equally to the work (ANB, HF, HG, FK, FNB, BNB).

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Correspondence to Afsaneh Naderi Beni.

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Naderi Beni, A., fesharaki, H., Ghanbari, H. et al. Clinical efficacy of inferior peripheral irido-capsulo-hyaloidotomy for pseudophakic malignant glaucoma. Int Ophthalmol 41, 3153–3161 (2021). https://doi.org/10.1007/s10792-021-01880-4

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  • DOI: https://doi.org/10.1007/s10792-021-01880-4

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