Abstract
Purpose
To evaluate the clinical outcomes of small incision lenticule extraction (SMILE) and aberration-free transepithelial photorefractive keratectomy (AF t-PRK) in patients with low to moderate myopic astigmatism, including visual acuity, refractive outcomes, astigmatic vector analysis and corneal aberrometric changes.
Method
This retrospective comparative case series study involved 110 right eyes of 110 patients who underwent either SMILE (55 eyes) or AF t-PRK (55 eyes). Visual acuity, manifest refractive error and corneal higher-order aberrations (HOAs) were measured and analyzed at baseline, 1 month and 3 months after operation. The safety and efficacy indices, and vector parameters were also compared.
Result
1 month postoperatively, the mean uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA) and spherical equivalent refraction (SE) were better after SMILE than AF t-PRK (logMAR UDVA, − 0.03 ± 0.07 and − 0.006 ± 0.07, P = 0.050; logMAR CDVA, − 0.06 ± 0.07 and − 0.03 ± 0.07, P = 0.043; SE, − 0.04 ± 0.25 and 0.15 ± 0.26, P < 0.001). However, these parameters were comparable between the groups at 3 months after surgery. Residual astigmatism ≤ 0.25 diopters was observed in 74.5% and 90.9% (P = 0.023) of the eyes at one month and in 87.3% and 85.5% (P = 0.781) of the eyes at 3 months after SMILE and AF t-PRK, respectively. There were no significant differences between the groups in any of the vector parameters at 1 month or 3 months after surgery. Coma and total HOAs after SMILE were significantly higher than AF t-PRK (1 month coma, 0.49 ± 0.23 and 0.29 ± 0.15, P < 0.001; 1 month total RMS HOAs, 0.65 ± 0.20 and 0.54 ± 0.14, P = 0.001; 3 months coma, 0.50 ± 0.22 and 0.30 ± 0.17, P < 0.001; 3 months total RMS HOAs, 0.68 ± 0.20 and 0.55 ± 0.17, P < 0.001).
Conclusion
In this study, both SMILE and AF t-PRK were effective and comparable for correction of low to moderate myopic astigmatism. AF t-PRK group induced less coma and total HOAs than SMILE.
Similar content being viewed by others
References
Fadlallah A, Fahed DS, Khalil K et al (2011) Transepithelial photorefractive keratectomy: clinical results [J]. J Cataract Refract Surg 37(10):1852–1857
Celik U, Bozkurt E, Celik B et al (2014) Pain, wound healing and refractive comparison of mechanical and transepithelial debridement in photorefractive keratectomy for myopia: Results of 1 year follow-up[J]. Contact Lens Anter Eye 37(6):420–426
Kaluzny BJ, Cieslinska I, Mosquera SA et al (2016) Single-step transepithelial PRK versus alcohol-assisted PRK in myopia and compound myopic astigmatism correction[J]. Medicine 95(6):e1993
Adib-Moghaddam S, Soleyman-Jahi S, Salmanian B, Omidvari AH, Adili-Aghdam F, Noorizadeh F et al (2016) Single-step transepithelial photorefractive keratectomy in myopia and astigmatism: 18-month follow-up[J]. J Cataract Refract Surg 42(11):1570–1578
Ivarsen A, Asp S, Hjortdal J (2014) Safety and complications of more than 1500? Small-incision lenticule extraction procedures[J]. Ophthalmology 121(4):822–828
Mrochen M, Schelling U, Wuellner C et al (2009) Influence of spatial and temporal spot distribution on the ocular surface quality and maximum ablation depth after photoablation with a 1050 Hz excimer laser system[J]. J Cataract Refract Surg 35(2):363–373
Ms LMS, Dickrell PL, Edelhauser HF et al (2008) Effects of laser repetition rate on corneal tissue ablation for 193-nm excimer laser light[J]. Lasers Surg Med 40(7):483–493
Ginis HS, Katsanevaki VJ, Pallikaris IG (2003) Inflfluence of ablation parameters on refractive changes after phototherapeutic keratectomy. J Refract Surg 19:443–448
He L, Manche EE (2015) Contralateral eye-to-eye comparison of wavefront-guided and wavefront-optimized photorefractive keratectomy: a randomized clinical trial[J]. Jama Ophthalmol 133(1):51–59
Myrowitz EH, Chuck RS (2009) A comparison of wavefront-optimized and wavefront-guided ablations[J]. Curr Opin Ophthalmol 20(4):247–250
Jun I, Kang DSY, Reinstein DZ et al (2018) Clinical outcomes of SMILE With a triple centration technique and corneal wavefront-guided transepithelial PRK in high astigmatism[J]. J Refract Surg 34(3):156–163
Arbelaez MC, Vidal C, Arba-Mosquera S (2010) Bilateral symmetry before and six months after aberration-free Correction with the SCHWIND AMARIS total tech laser: clinical outcomes[J]. J Optom 3(1):20–28
Ivarsen A, Asp S, Hjortdal J (2014) Safety and complications of more than 1500 small-incision lenticule extraction procedures[J]. Ophthalmology 121(4):822–828
De Ortueta D, von Rüden D, Verma S et al (2018) Transepithelial photorefractive keratectomy in moderate to high astigmatism with a non-wavefront-guided aberration-neutral ablation profile[J]. J Refract Surg 34:466–474
Jun I, Kang DSY, Tan J et al (2017) Comparison of clinical outcomes between wavefront-optimized versus corneal wavefront-guided transepithelial photorefractive keratectomy for myopic astigmatism[J]. J Cataract Refract Surg 43(2):174–182
Kepez YB, Ufuk U, Goksel UM et al (2018) Correction of myopic astigmatism by small incision lenticule extraction: does laterality matter?[J]. Lasers Med Sci 34:311–316
Ikhyun J, Yong KDS, Samuel AM et al (2018) Comparison between wavefront-optimized and corneal wavefront-guided transepithelial photorefractive keratectomy in moderate to high astigmatism[J]. BMC Ophthalmol 18(1):154
Antonios R, Fattah MA, Mosquera SA et al (2017) Single-step transepithelial versus alcohol-assisted photorefractive keratectomy in the treatment of high myopia: a comparative evaluation over 12 months[J]. Br J Ophthalmol 101(8):1106–1112
Adib-Moghaddam S, Soleyman-Jahi S, Adili-Aghdam F, Arba Mosquera S, Hoorshad N, Tofighi S (2017) Single-step transepithelial photorefractive keratectomy in high myopia:qualitative and quantitative visual functions[J]. Int J Ophthalmol 03:121–128
Piñero DP, Teus MA (2016) Clinical outcomes of small-incision lenticule extraction and femtosecond laser–assisted wavefront-guided laser in?situ?keratomileusis[J]. J Cataract Refract Surg 42(7):1078–1093
Zhang J, Wang Y, Chen X (2016) Comparison of moderate- to high-astigmatism corrections using wavefront–guided laser in situ keratomileusis and small-incision lenticule extraction[J]. Cornea 35(4):523
Kang DSY, Lee H, Reinstein DZ et al (2018) Comparison of the distribution of lenticule decentration following smile by subjective patient fixation or triple marking centration[J]. J Refract Surg 34(7):446
Teus MA, Montserrat GG, Fangyu L et al (2014) Comparison of the visual results after small incision lenticule extraction and femtosecond laser-assisted LASIK for myopia[J]. J Refract Surg 30(9):582–582
Ağca A, Demirok A, Cankaya Kİ et al (2014) Comparison of visual acuity and higher-order aberrations after femtosecond lenticule extraction and small-incision lenticule extraction[J]. Contact Lens Anter Eye 37(4):292–296
Sekundo W, Gertnere J, Bertelmann T et al (2014) One-year refractive results, contrast sensitivity, high-order aberrations and complications after myopic small-incision lenticule extraction (ReLEx SMILE)[J]. Graefe Arch Clin Exp Ophthalmol 252(5):837–843
Yildirim Y, Olcucu O, Alagoz C et al (2016) Visual and refractive outcomes of photorefractive keratectomy and small incision lenticule extraction (SMILE) for Myopia[J]. J Refract Surg 32(9):604
Funding
This study was funded by Science and Technology Project of Shantou City, Guangdong, China (2019-106).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Ethical approval
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent
Informed consent was obtained from all individual participants included in the study.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Zheng, Z., Zhang, M., Jhanji, V. et al. Comparison between aberration-free transepithelial photorefractive keratectomy and small incision lenticule extraction for correction of myopia and myopic astigmatism. Int Ophthalmol 41, 303–314 (2021). https://doi.org/10.1007/s10792-020-01582-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10792-020-01582-3