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Posterior staphylomas in non-highly myopic eyes with retinitis pigmentosa

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Abstract

Purpose

Our aim was to highlight the presence and the frequency of posterior staphyloma (PS) in non-highly myopic retinitis pigmentosa (RP) patients and to study the relationship between PS and choroidal thickness (CT).

Methods

This was a retrospective case–control study of 77 eyes (39 patients) with RP, axial length inferior to 26 mm and clinically preserved macular area. All patients underwent fundus photography, A- and B-scan ocular ultrasonography, fundus autofluorescence (FAF) and swept source optical coherence tomography (SS-OCT). PS was defined by an outward bowing of the sclera on SS-OCT and B-scans. The relationship between the PS and SS-OCT layers thicknesses was determined.

Results

Over 77 RP eyes of 39 patients studied, a PS was identified in 17 eyes (22%) of nine patients. Fifteen eyes had a narrow macular staphyloma (NMS), and two eyes had a wide macular staphyloma (WMS). Mean age in this group was 34.2 years (range 19–53 years), mean axial length was 23.60 ± 0.61 mm and mean CT was 185.7 ± 71 um versus 259.7 um in eyes without PS. The staphyloma edges corresponded to area of outer retina loss on SS-OCT and were larger than the hyperautofluorescent ring on FAF.

We found a significant association between PS and CT in our RP patients (p = 0.003).

The mean CT was significantly thinner in PS eyes compared to eyes without staphyloma. There was no significant association between PS and with visual acuity, years of progression, retinal thickness nor FAF findings.

Conclusions

PS was present in 22% of non-highly myopic eyes with RP. Narrow macular staphyloma was the most common type observed in our series. A marked thinning of the choroid was noted in PS eyes when compared to RP eyes without PS, as well as the outer retina degeneration.

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Acknowledgements

The Tunisian Ministry of Public Health and the Ministry of Higher Education and Scientific Research (LR14 SP01) supported this work.

Funding

The author(s) received no financial support for the research, authorship and/or publication of this article.

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Authors and Affiliations

  1. Oculogenetic Laboratory LR14SP01, Tunis El Manar University, Tunis, Tunisia

    Leila El Matri, Yousra Falfoul, Khaled El Matri, Issam El Euch, Asma Hassairi, Nibrass Chaker & Ahmed Chebil

  2. B Department, Hedi Rais Institute of Ophthalmology, Faculty of Medicine of Tunis, Tunis, Tunisia

    Leila El Matri, Yousra Falfoul, Khaled El Matri, Asma Hassairi, Nibrass Chaker & Ahmed Chebil

  3. Department of Family and Community Medicine, Faculty of Medicine Ibn El Jazzar, Sousse, Tunisia

    Hela Ghali

  4. IRO-Institute for Research in Ophthalmology, Sion, Switzerland

    Imen Habibi & Daniel Schorderet

Authors
  1. Leila El Matri
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  2. Yousra Falfoul
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  3. Khaled El Matri
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  4. Issam El Euch
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  8. Nibrass Chaker
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  10. Ahmed Chebil
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Correspondence to Yousra Falfoul.

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The author(s) declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article.

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The Local Ethics Committee of the Hedi Rais Institute of Ophthalmology of Tunis, Tunisia, approved this work.

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El Matri, L., Falfoul, Y., El Matri, K. et al. Posterior staphylomas in non-highly myopic eyes with retinitis pigmentosa. Int Ophthalmol 40, 2159–2168 (2020). https://doi.org/10.1007/s10792-020-01396-3

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  • DOI: https://doi.org/10.1007/s10792-020-01396-3

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