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Outcome of sutured scleral fixated intraocular lens in Marfan syndrome in pediatric eyes

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Abstract

Purpose

To report the clinical outcomes and complications in eyes with Marfan syndrome with subluxated/dislocated lens undergoing sutured scleral fixated intraocular lens (SSFIOL) implantation.

Methods

A retrospective review was done for a consecutive series of 73 eyes of 43 patients with Marfan syndrome, with age less than 18 years who underwent SSFIOL from July 2000 to June 2017. Postoperative best corrected visual acuity, intraocular pressure and refractive error, intraoperative and postoperative complications and time for the development of these complications were analyzed.

Results

Visual acuity improved significantly to 0.43 ± 0.30 (p = 0.01), 0.40 ± 0.3 (p = 0.00) and 0.39 ± 0.3 (p = 0.00) logMAR units at 6 weeks, 1 year and at last follow-up, respectively. The refractive error reduced significantly (p = 0.056, 0.039 and 0.031) at 6 weeks, 1 year and final follow-up following surgery. Intraoperative complications included iatrogenic retinal break (n = 3) and surgical trauma to the iris (n = 1). Postoperative complications included increased intraocular pressure in 3 eyes (4.1%), intraocular lens dislocation/subluxation in 5 eyes (6.8%), retinal detachment in 3 eyes (4.1%), choroidal detachment in 1 eye (1.3%), pupillary capture in 15 eyes (20.5%), vitreous hemorrhage in 1 eye (1.3%), pre-retinal hemorrhage in 1 eye (1.3%) and hyphema in 1 eye (1.3%).

Conclusion

SSFIOL provides good visual outcomes in eyes with ectopia lentis associated with Marfan syndrome. Complications can be seen in some cases, and the parents need to be counseled regarding the same before surgical intervention.

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Acknowledgements

We acknowledge the contributions of Mr. Vishwanathan, Department of Biostatistics, Medical Research Foundation, Sankara Nethralaya, Chennai, for his contribution to statistics in this manuscript.

Funding

There was no involvement by any funding body.

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Authors and Affiliations

  1. Shri Bhagwan Mahavir Vitreo-Retinal Services, Medical Research Foundation, Sankara Nethralaya, 18-College Road, Nungambakkam, Chennai, Tamil Nadu, 600006, India

    Parveen Sen, Yamini Attiku, Pramod Bhende, Ekta Rishi, Dhanashree Ratra & Kummamuri Sreelakshmi

Authors
  1. Parveen Sen
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  2. Yamini Attiku
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  3. Pramod Bhende
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  4. Ekta Rishi
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  5. Dhanashree Ratra
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  6. Kummamuri Sreelakshmi
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Correspondence to Parveen Sen.

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All procedures performed in the study were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Sen, P., Attiku, Y., Bhende, P. et al. Outcome of sutured scleral fixated intraocular lens in Marfan syndrome in pediatric eyes. Int Ophthalmol 40, 1531–1538 (2020). https://doi.org/10.1007/s10792-020-01322-7

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  • DOI: https://doi.org/10.1007/s10792-020-01322-7

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