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Ocular manifestations in celiac disease: an overview

A Correction to this article was published on 02 April 2020

This article has been updated

Abstract

Purpose

To review and highlight the ocular manifestations associated with celiac disease (CD) and presentation of their pathogenetic mechanisms.

Methods

A thorough review of the literature was performed using PubMed to identify articles about serrated polyposis syndrome. The search was performed using the search string: (“celiac disease” OR “coeliac disease”) AND (“ocular manifestations” OR “eye” OR “orbitopathy” OR “uveitis” OR “neuro-ophthalmic manifestations”). Only articles in English were reviewed.

Results

Several ocular symptoms and disorders have been associated with CD and are a result of defective intestinal absorption and immunological mechanisms. These include nyctalopia, dry eye, cataract, thyroid-associated orbitopathy, uveitis, central retinal vein occlusion and neuro-ophthalmic manifestations. In addition, CD-related ocular disease may represent the first manifestation of CD.

Conclusion

CD may hold accountable for the development of ocular diseases of obscure etiology.

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Change history

  • 02 April 2020

    In the original publication, first line of <Emphasis Type="Italic">methods</Emphasis> under the Abstract section was published incorrectly.

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Correspondence to Dimitrios K. Christodoulou.

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Fousekis, F.S., Katsanos, A., Katsanos, K.H. et al. Ocular manifestations in celiac disease: an overview. Int Ophthalmol 40, 1049–1054 (2020). https://doi.org/10.1007/s10792-019-01254-x

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Keywords

  • Extraintestinal manifestations
  • Celiac disease
  • Celiac disease
  • Eye
  • Uveitis
  • Dry eye