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Investigating the effects of glaucomatous damage on the multifocal visual evoked potential parameters

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Abstract

Purpose

To investigate the effects of glaucomatous damage on the mfVEP parameters of patients suffering from primary open-angle glaucoma (POAG).

Methods

Fifteen healthy subjects and 15 patients with unilateral POAG participated in this study. In addition, routine ophthalmological examinations including visual acuity, anterior segment examination, posterior segment examination, intraocular pressure, mfVEP with electrophysiological system, RETI-port/Scan 21, and visual field test with automated Humphrey ZEISS HFA II 750i Perimeter were also performed.

Results

The results show that there was a strong correlation between the ∆MDs and the number of abnormal points with the ∆amplitudes more than 256 nV, in patients (n = 15, r = 0.802, p < 0.05), but no correlations were found between the mean sensitivity differences (ΔPSDs) and mfVEP parameters.

Conclusions

Comparing the monocular mfVEP responses from both eyes is an appropriate method to detect unilateral damage. Achievement of more development and making the mfVEP test more functional can be a solution for early diagnosis in most of the eye diseases.

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Acknowledgements

The authors would like to thankfully acknowledge the financial support of the Vice Chancellor of Research Affairs of Ahvaz Jundishapur University of Medical Sciences (330093897). This paper was issued from the MSc thesis of Parvin Armiun. The authors thank Dr Niloofar Neisi for helping with the manuscript writing.

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Authors and Affiliations

  1. Department of Medical Physics, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

    Amir Danyaei, Parvin Armiun & Mohammad Javad Tahmasebi

  2. Department of Ophthalmology, Faculty of Medicine, Ophthalmology Research Center, Jundishapur University of Medical Sciences, Ahvaz, Iran

    Ali Kasiri

  3. Department of Health School, Faculty of Health School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

    Seyed Mahmoud Latifi

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  1. Amir Danyaei
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  2. Ali Kasiri
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  4. Parvin Armiun
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Correspondence to Parvin Armiun.

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Danyaei, A., Kasiri, A., Latifi, S.M. et al. Investigating the effects of glaucomatous damage on the multifocal visual evoked potential parameters. Int Ophthalmol 39, 2897–2904 (2019). https://doi.org/10.1007/s10792-019-01138-0

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  • DOI: https://doi.org/10.1007/s10792-019-01138-0

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