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Comparison of Samfilcon A and Lotrafilcon B silicone hydrogel bandage contact lenses in reducing postoperative pain and accelerating re-epithelialization after photorefractive keratectomy

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Abstract

Purpose

To compare the efficacy of Samfilcon A and Lotrafilcon B bandage contact lenses after photorefractive keratectomy (PRK).

Methods

In this study, patients with bilateral PRK were assigned for the fitting of Lotrafilcon B lens and Samfilcon A lens. The patients were examined on the day of surgery and on postoperative days 1, 2 and 3. Slit biomicroscopy was performed to assess epithelial defect size in the postoperative examinations. The subjective evaluation of pain and visual symptoms was recorded on postoperative days 1, 2 and 3.

Results

Analysis was made of 68 eyes of 34 patients who fulfilled the criteria and had PRK for correction of low to moderate myopia/astigmatism. On postoperative days 1 and 2, pain and epiphora scores were significantly lower in eyes with Samfilcon A lens (p < 0.001 for all), and on postoperative day 3, the differences were not significant (p = 0.414 and p = 0.180, respectively). There was no significant difference between the two lenses in respect of the levels of photophobia. The difference in epithelial defect size was statistically lower in eyes with Samfilcon A lens compared to Lotrafilcon B on day 1 (16.89 mm2 vs. 21.07 mm2; p = 0.003) and day 2 (1.49 mm2 vs. 2.46 mm2; p < 0.001). The difference was not significant on day 3. (0.05 mm2 vs. 0.05 mm2; p = 1.000).

Conclusions

The Samfilcon A lens is superior to the Lotrafilcon B lens in reducing postoperative pain and accelerating re-epithelialization.

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Authors and Affiliations

  1. Ophthalmology Department, Faculty of Medicine, Kastamonu University, Alacaatlı Mah. Sinpas Incek Life Kon. 2/5, Kastamonu, Turkey

    Erdem Yuksel

  2. Ophthalmology Department, Tobb-Etu University Hospital, Ankara, Turkey

    Kemal Ozulken

  3. Ophthalmology Department, Afyonkarahisar State Hospital, Afyonkarahisar, Turkey

    Mehmet Murat Uzel

  4. Ophthalmology Department, Afyonkarahisar Sandıklı State Hospital, Afyonkarahisar, Turkey

    Ayse Guzin Taslipinar Uzel

  5. Ophthalmology Department, World Eye Hospital, Ankara, Turkey

    Semih Aydoğan

Authors
  1. Erdem Yuksel
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  2. Kemal Ozulken
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  3. Mehmet Murat Uzel
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  4. Ayse Guzin Taslipinar Uzel
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  5. Semih Aydoğan
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Correspondence to Erdem Yuksel.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Yuksel, E., Ozulken, K., Uzel, M.M. et al. Comparison of Samfilcon A and Lotrafilcon B silicone hydrogel bandage contact lenses in reducing postoperative pain and accelerating re-epithelialization after photorefractive keratectomy. Int Ophthalmol 39, 2569–2574 (2019). https://doi.org/10.1007/s10792-019-01105-9

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  • DOI: https://doi.org/10.1007/s10792-019-01105-9

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