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Chorioretinal folds: a proposed diagnostic algorithm

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Abstract

Purpose

To create a diagnostic algorithm for the management of chorioretinal folds.

Methods

We reviewed the existing literature about chorioretinal folds focusing our attention on three specific conditions and created a diagnostic algorithm in order to otpimize the choice and the number of investigations.

Results

Chorioretinal folds are visible striations of the fundus usually arranged in parallel lines and disposed horizontally. They may be either unilateral or bilateral, symptomatic or asymptomatic and are often associated with different possible ocular and extra ocular pathologies, including systemic diseases like autoimmune disorders and intracranial hypertension. They are named idiopathic when no apparent cause for their development is detectable. However, with improved diagnostic testing, the patients with idiopathic choroidal folds are likely to represent only a smaller portion of the total.

Conclusions

Since choroidal folds be the sole sign of an underlying disease possibly requiring a multidisciplinary approach, an appropriate work-up varying according to the specific clinical features of each case is needed to define the etiology and the treatment. A diagnosting algorithm may be useful in order to optimize the diagnostic approach and management.

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References

  1. Agarwal A (2011) Gass’ atlas of macular diseases, 5th edn. Elsevier Health Sciences, Amsterdam

    Google Scholar 

  2. Leahey AB, Brucker AJ, Wyszynski RE, Shaman P (1993) Chorioretinal folds. A comparison of unilateral and bilateral cases. Arch Ophthalmol Chic Ill 111:357–359

    Article  CAS  Google Scholar 

  3. Friberg TR (1989) The etiology of choroidal folds. A biomechanical explanation. Graefes Arch Clin Exp Ophthalmol 227:459–464

    Article  CAS  Google Scholar 

  4. Nettleship E (1884) Peculiar lines in the choroid in a case papillitic atrophy. Ophthalmol Soc U K 4:167–168

    Google Scholar 

  5. Cangemi FE, Trempe CL, Walsh JB (1978) Choroidal folds. Am J Ophthalmol 86:380–387. https://doi.org/10.1016/0002-9394(78)90243-X

    Article  CAS  PubMed  Google Scholar 

  6. Cohen SM, Gass JDM (1994) Bilateral radial chorioretinal folds. Int Ophthalmol 18:243–245. https://doi.org/10.1007/BF00951806

    Article  PubMed  Google Scholar 

  7. Denniston A, Murray P (2009) Oxford handbook of ophthalmology, 2nd edn. Oxford University Press, Oxford, New York

    Google Scholar 

  8. Md PKK, Md NJF, Md RPII (2014) The Massachusetts eye and ear infirmary illustrated manual of ophthalmology, 4th edn. Saunders, Philadelphia

    Google Scholar 

  9. Griebel SR, Kosmorsky GS (2000) Choroidal folds associated with increased intracranial pressure. Am J Ophthalmol 129:513–516

    Article  CAS  Google Scholar 

  10. Lavinsky J, Lavinsky D, Lavinsky F, Frutuoso A (2007) Acquired choroidal folds: a sign of idiopathic intracranial hypertension. Graefes Arch Clin Exp Ophthalmol Albrecht Von Graefes Arch Klin Exp Ophthalmol 245:883–888. https://doi.org/10.1007/s00417-006-0455-7

    Article  Google Scholar 

  11. Kim KY, Kwak H-W, Kim M, Yu S-Y (2013) Traumatic chorioretinal folds treated with intra-vitreal triamcinolone injection. Indian J Ophthalmol 61:179–182. https://doi.org/10.4103/0301-4738.112165

    Article  PubMed  PubMed Central  Google Scholar 

  12. Söylev MF, Saatci O, Saatci I et al (1996) Choroidal folds associated with a sellar mass. Int Ophthalmol 20:259–261. https://doi.org/10.1007/BF00131920

    Article  PubMed  Google Scholar 

  13. Ernst BB, Lowder CY, Meisler DM, Gutman FA (1991) Posterior segment manifestations of inflammatory bowel disease. Ophthalmology 98:1272–1280. https://doi.org/10.1016/S0161-6420(91)32143-2

    Article  CAS  PubMed  Google Scholar 

  14. Grinager HS, Krason DA, Olsen TW (2012) Lyme disease: resolution of a serous retinal detachment and chorioretinal folds after antibiotic therapy. Retin Cases Brief Rep 6:232–234. https://doi.org/10.1097/ICB.0b013e3182247783

    Article  PubMed  Google Scholar 

  15. Krist D, Wenkel H (2002) Posterior scleritis associated with Borrelia burgdorferi (Lyme disease) infection. Ophthalmology 109:143–145

    Article  Google Scholar 

  16. Leventer DB, Linberg JV (1960) Ellis B (2001) Frontoethmoidal mucoceles causing bilateral chorioretinal folds. Arch Ophthalmol Chic Ill 119:922–923

    Article  Google Scholar 

  17. Taban M, Kosmorsky GS, Singh AD, Sears JE (2007) Choroidal folds secondary to parasellar meningioma. Eye Lond Engl 21:147–150. https://doi.org/10.1038/sj.eye.6702479

    Article  CAS  Google Scholar 

  18. Kalina RE, Mills RP (1980) Acquired hyperopia with choroidal folds. Ophthalmology 87:44–50

    Article  CAS  Google Scholar 

  19. Gass’ Atlas of Macular Diseases, 5th edn. https://www.elsevier.com/books/gass-atlas-of-macular-diseases/agarwal/978-1-4377-1580-4. Accessed 14 Nov 2017

  20. Murdoch D, Merriman M (2002) Acquired hyperopia with choroidal folds. Clin Experiment Ophthalmol 30:292–294

    Article  Google Scholar 

  21. Olsen TW, Palejwala NV, Lee LB et al (2014) Chorioretinal folds: associated disorders and a related maculopathy. Am J Ophthalmol 157:1038–1047. https://doi.org/10.1016/j.ajo.2014.02.021

    Article  PubMed  Google Scholar 

  22. Fannin LA, Schiffman JC, Budenz DL (2003) Risk factors for hypotony maculopathy. Ophthalmology 110:1185–1191. https://doi.org/10.1016/S0161-6420(03)00227-6

    Article  PubMed  Google Scholar 

  23. Schubert HD (1996) Postsurgical hypotony: relationship to fistulization, inflammation, chorioretinal lesions, and the vitreous. Surv Ophthalmol 41:97–125

    Article  CAS  Google Scholar 

  24. Thomas M, Vajaranant TS, Aref AA (2015) Hypotony maculopathy: clinical presentation and therapeutic methods. Ophthalmol Ther 4:79–88. https://doi.org/10.1007/s40123-015-0037-z

    Article  PubMed  PubMed Central  Google Scholar 

  25. Rivara A, Zingirian M (1968) Volume du bulbe et rigidité sclérale. Ophthalmologica 156:394–398. https://doi.org/10.1159/000305482

    Article  CAS  PubMed  Google Scholar 

  26. Benson WE (1988) Posterior scleritis. Surv Ophthalmol 32:297–316

    Article  CAS  Google Scholar 

  27. Cavallini GM, Volante V, Bigliardi MC et al (2014) Bilateral posterior scleritis as a presenting manifestation of giant cell arteritis: a case report. Can J Ophthalmol J Can Ophtalmol 49:e141–e143. https://doi.org/10.1016/j.jcjo.2014.08.015

    Article  Google Scholar 

  28. McCluskey PJ, Watson PG, Lightman S et al (1999) Posterior scleritis: clinical features, systemic associations, and outcome in a large series of patients. Ophthalmology 106:2380–2386. https://doi.org/10.1016/S0161-6420(99)90543-2

    Article  CAS  PubMed  Google Scholar 

  29. Onal S, Tugal-Tutkun I, Neri P, Herbort CP (2014) Optical coherence tomography imaging in uveitis. Int Ophthalmol 34:401–435. https://doi.org/10.1007/s10792-013-9822-7

    Article  PubMed  Google Scholar 

  30. Haruyama M (2001) Indocyanine green angiographic findings of chorioretinal folds. Jpn J Ophthalmol 45:293–300. https://doi.org/10.1016/S0021-5155(01)00323-9

    Article  CAS  PubMed  Google Scholar 

  31. Del Turco C, Rabiolo A, Carnevali A et al (2017) Optical coherence tomography angiography features of chorioretinal folds: a case series. Eur J Ophthalmol 27:35–38. https://doi.org/10.5301/ejo.5000872

    Article  Google Scholar 

  32. Musetti D, Nicolò M, Bagnis A, Traverso CE (2014) Chorioretinal folds: associated disorders and a related maculopathy. Am J Ophthalmol 158:409. https://doi.org/10.1016/j.ajo.2014.05.005

    Article  PubMed  Google Scholar 

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Correspondence to Alessandro Bagnis.

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Bagnis, A., Cutolo, C.A., Corallo, G. et al. Chorioretinal folds: a proposed diagnostic algorithm. Int Ophthalmol 39, 2667–2673 (2019). https://doi.org/10.1007/s10792-019-01083-y

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