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Correlation between central corneal thickness and myopia

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Abstract

Purpose

To analyze the correlation between central corneal thickness (CCT) and myopia in refractive surgery candidates.

Materials and methods

Patients that underwent myopic laser refractive surgery between January 2000 and December 2014 were included. Preoperative CCT was measured by ultrasonic pachymetry, and refractive status determined by manifest and cycloplegic refraction.

Results

A total of 30,245 individuals were included. Mean age was 28.2 ± 8.6 years, and 45.9% were female. Mean refractive error was 4.02 ± 2.17 D (range 0.25–19.5), and the mean CCT measurement was 533.5 ± 35.5 µm (range 404–794). Younger individuals showed higher degree of myopia (p = 0.006). No difference in CCT was found between women and men (533.0 ± 35.1 and 533.6 ± 35.9 µm, respectively, p = 0.19). Though CCT showed no correlation with age (p = 0.226) participants above age 40 expressed higher CCT values (p < 0.001). No significant correlation was found between the CCT and cylinder (p > 0.05). An increase in mean keratometry was associated with a decrease in CCT (p < 0.001). There was a direct correlation between the degree of myopia and CCT (r = 0.94, p < 0.001). The result remained the same after adjusting for age group and gender in stepwise backward regression analysis (p < 0.001).

Conclusion

Central corneal thickness is correlated with the degree of myopia among adults undergoing refractive surgery.

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Author notes

  1. Michael Mimouni and Victor Flores have contributed equally to this paper.

Authors and Affiliations

  1. Department of Ophthalmology, Rambam Health Care Campus, Technion-Israel Institute of Technology, Haifa, Israel

    Michael Mimouni, Victor Flores, Yinon Shapira & Shmuel Graffi

  2. Department of Ophthalmology, Barzilai Medical Center, Ashkelon and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheba, Israel

    Shmuel Levartovsky & Igor Kaiserman

  3. Care-Vision Laser Centers, Tel Aviv, Israel

    Tzahi Sela, Gur Munzer & Igor Kaiserman

Authors
  1. Michael Mimouni
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  2. Victor Flores
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  3. Yinon Shapira
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  4. Shmuel Graffi
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  5. Shmuel Levartovsky
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  6. Tzahi Sela
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  7. Gur Munzer
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  8. Igor Kaiserman
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Contributions

All authors substantially contributed to this study.

Corresponding author

Correspondence to Michael Mimouni.

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The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

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Mimouni, M., Flores, V., Shapira, Y. et al. Correlation between central corneal thickness and myopia. Int Ophthalmol 38, 2547–2551 (2018). https://doi.org/10.1007/s10792-017-0766-1

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  • DOI: https://doi.org/10.1007/s10792-017-0766-1

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