Listeria monocytogenes and ocular abscess: an atypical but yet potential association

  • Coline Legendre
  • Hélène Hannetel
  • Anne-Gaëlle Ranc
  • Widad Bezza
  • Laurence Pages
  • François Vandenesch
  • Anne Tristan
  • Anne Doleans-Jordheim
Case Report
  • 38 Downloads

Abstract

Purpose

To report a farmer’s corneal abscess caused by an unusual pathogen: Listeria monocytogenes fluoroquinolone resistant.

Methods

A 78-year-old farmer presented a central corneal abscess associated with 1-mm hypopyon and decreased visual acuity evolving since 2 weeks. First an antibiotic therapy associating oral ofloxacin and topical ciprofloxacin, vancomycin and ceftazidime was started. Different samples of the abscess were performed and sent to different microbiological laboratories.

Result

Listeria monocytogenes was isolated after 2 days of culture. Antibiotics sensitivity showed resistance to ciprofloxacin, fosfomycin and fusidic acid. Ceftazidime was changed for gentamicin, and after 1 month of treatment the abscess decreased considerably.

Conclusion

This case demonstrated that even if Listeria is rarely involved in ocular abscess, it must be evocated for people with risk factors as farmers. This suspicion should lead to an extended incubation to identify the pathogen. The analysis of Listeria resistance is essential to start an efficient therapy.

Keywords

Ocular abscess Listeria monocytogenes Risk factors Resistance 

Notes

Compliance with ethical standards

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

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Copyright information

© Springer Science+Business Media B.V. 2017

Authors and Affiliations

  • Coline Legendre
    • 1
  • Hélène Hannetel
    • 1
  • Anne-Gaëlle Ranc
    • 1
    • 2
    • 3
  • Widad Bezza
    • 4
  • Laurence Pages
    • 5
  • François Vandenesch
    • 1
    • 6
    • 7
  • Anne Tristan
    • 1
    • 6
    • 7
  • Anne Doleans-Jordheim
    • 1
    • 5
    • 8
  1. 1.Laboratory of Microbiology, Groupement Hospitalier EstHospices Civils de LyonBronFrance
  2. 2.French Reference Center for Legionella, Laboratory of Microbiology, Groupement Hospitalier EstHospices Civils de LyonBronFrance
  3. 3.CIRI, International Center of Infectious Research, INSERM U1111, CNRS UMR5308University of Lyon 1, ENS de LyonLyonFrance
  4. 4.Ophthalmology Department, Hôpital Edouard HerriotHospices Civils de LyonLyonFrance
  5. 5.Research Group on «Bacterial Opportunistic Pathogens and Environment», UMR 5557 Ecologie Microbienne, CNRSUniversity of Lyon 1, ENVLLyonFrance
  6. 6.French Reference Center for Staphylococci, Laboratory of Microbiology, Groupement Hospitalier EstHospices Civils de LyonBronFrance
  7. 7.CIRI, International Center for Infectiology Research, INSERM U851University of Lyon 1LyonFrance
  8. 8.Groupe de Recherche “Bactéries pathogènes opportunistes et environnement”, UMR 5557 Ecologie Microbienne, Laboratoire de Mycologie-Microbiologie (Pavillon Nétien 3ème étage), Faculté de Pharmacie-ISPBUniversité Claude Bernard Lyon 1Lyon Cedex 08France

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