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Visual acuity and corneal higher-order aberrations after EX-PRESS or trabeculectomy, and the determination of associated factors that influence visual function

International Ophthalmology volume 38, pages 1969–1976 (2018)Cite this article

Abstract

Purpose

This study investigated postoperative visual acuity and corneal higher-order aberrations following EX-PRESS or trabeculectomy.

Methods

Out of 56 eyes of 56 patients analyzed, 30 eyes were treated using trabeculectomy, while 26 eyes were treated with EX-PRESS. Visual acuity and corneal higher-order aberrations were analyzed in both groups before and at 2 weeks, 1, 2, and 3 months after the surgeries. Risk factors that could potentially influence corneal higher-order aberrations were evaluated.

Results

Significant reductions in the IOP were observed at 3 months after the surgery in both groups. Although a significant decrease in the visual acuity (logMAR) was observed at 2 weeks after the surgery in both groups, at 1 month after the surgeries, there were no significant differences found for the vision as compared to the baseline. At each study visit in the trabeculectomy group, significantly higher corneal higher-order aberrations compared to baseline were noted. In the EX-PRESS group, however, these aberrations were no longer significantly different from the baseline at month 2 (P = 0.36). Analysis of the risk factors indicated that hypotony could influence corneal higher-order aberrations after surgery.

Conclusions

Corneal higher-order aberrations were significantly increased at 1 month after EX-PRESS treatment, with levels returning to baseline by 2 months. After trabeculectomy, however, corneal higher-order aberrations remained significantly increased at 3 months after the procedure.

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Fig. 1

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Acknowledgements

This work was supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (26462689).

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Affiliations

  1. Department of Ophthalmology, Kagawa University Faculty of Medicine, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan

    Nobuko Kobayashi, Kazuyuki Hirooka, Eri Nitta, Kaori Ukegawa & Akitaka Tsujikawa

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  1. Nobuko Kobayashi
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  2. Kazuyuki Hirooka
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  3. Eri Nitta
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  4. Kaori Ukegawa
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  5. Akitaka Tsujikawa
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Corresponding author

Correspondence to Kazuyuki Hirooka.

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All authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Cite this article

Kobayashi, N., Hirooka, K., Nitta, E. et al. Visual acuity and corneal higher-order aberrations after EX-PRESS or trabeculectomy, and the determination of associated factors that influence visual function. Int Ophthalmol 38, 1969–1976 (2018). https://doi.org/10.1007/s10792-017-0685-1

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Keywords

  • Trabeculectomy
  • EX-PRESS
  • Higher-order aberrations
  • Visual acuity