Abstract
Purpose
This study was aimed to assess the long-term results of phacoemulsification and posterior chamber intraocular lens implantation in patients with anterior uveitis.
Methods
Patients with complicated cataract secondary to anterior uveitis who underwent phacoemulsification and posterior chamber intraocular lens implantation were included in this study. Long-term results and all complications were evaluated throughout the postoperative 4 years.
Results
A total of 55 eyes of 48 patients were identified in this study. Cases with anterior uveitis were categorised into four aetiologic groups. Of the 55 eyes, 22 (19 patients) had idiopathic anterior uveitis, 10 (9 patients) had viral anterior uveitis, 10 (9 patients) had Fuchs’ anterior uveitis and 13 (11 patients) had anterior uveitis associated with collagen vascular diseases. Preoperative macular oedema was more frequent (63.6%) in the idiopathic group than in the other groups (p < 0.001). The success rates of the best corrected visual acuity of 20/40 or better ranged from 80.0 to 100.0% in the groups. While postoperative increased intraocular pressure rate was statistically significantly higher in the Fuchs’ group (p = 0.047), there was no statistically significant difference in other complication rates between the groups.
Conclusions
The long-term outcomes of phacoemulsification with intraocular lens implantation in patients with uveitic cataract were satisfactory with excellent visual acuity and relatively low complication rates.
Similar content being viewed by others
Abbreviations
- BCVA:
-
Best corrected visual acuity
- IOL:
-
Intraocular lens implantation
- PCIOL:
-
Posterior chamber intraocular lens implantation
- IOP:
-
Intraocular pressure
- OCT:
-
Optic coherence tomography
- CME:
-
Cystoid macular oedema
- FFA:
-
Fundus fluorescein angiography
- HSV:
-
Herpes simplex virus
- PCO:
-
Posterior capsule opacification
- Nd:YAG:
-
Nd:YAG (neodymium-doped yttrium aluminium garnet)
- ERM:
-
Epiretinal membrane
References
Jr LTC (2010) Surgical anatomy, biochemistry, pathogenesis, and classification of cataracts. In: Steinert RF (ed) Cataract surgery, 3rd edn. Saunders, Philadelphia
Pascolini D, Mariotti SP (2012) Global estimates of visual impairment: 2010. Br J Ophthalmol 96(5):614–618
Klein BE, Klein R, Knudtson MD (2006) Lens opacities associated with performance-based and self-assessed visual functions. Ophthalmology 113:1257–1263
Sheppard JD Jr, Nguyen QD, Usner DW, Comstock TL (2012) Post-cataract outcomes in patients with noninfectious posterior uveitis treated with the fluocinolone acetonide intravitreal implant. Clin Ophthalmol 6:79–85
Jancevski M, Foster CS (2010) Cataracts and uveitis. Curr Opin Ophthalmol 21:10–14
Mehta S, Linton MM, Kempen JH (2014) Outcomes of cataract surgery in patients with uveitis: a systematic review and meta-analysis. Am J Ophthalmol 158(676–692):e7
Lobo AM, Papaliodis GN (2010) Perioperative evaluation and management of cataract surgery in uveitis patients. Int Ophthalmol Clin 50:129–137
Elgohary MA, McCluskey PJ, Towler HMA et al (2007) Outcome of phacoemulsification in patients with uveitis. Br J Ophthalmol 91:916–1021
Kosker M, Sungur G, Celik T et al (2013) Phacoemulsification with intraocular lens implantation in patients with anterior uveitis. J Cataract Refract Surg 39:1002–1007
Van Gelder RN, Leveque TK (2009) Cataract surgery in the setting of uveitis. Curr Opin Ophthalmol 20:42–45
Mehta S, Kempen JH (2015) Cataract surgery in patients with uveitis. Int Ophthalmol Clin 55:133–139
Murthy SI, Pappuru RR, Latha KM et al (2013) Surgical management in patient with uveitis. Indian J Ophthalmol 61:284–290
Jones NP (2015) The Manchester Uveitis Clinic: the first 3000 patients—epidemiology and casemix. Ocul Immunol Inflamm 23:118–126
Sen HN, Vitale S, Gangaputra SS et al (2014) Periocular corticosteroid injections in uveitis: effects and complications. Ophthalmology 121:2275–2286
Engelhard SB, Haddad Z, Bajwa A et al (2015) Infectious uveitis in Virginia. Clin Ophthalmol 9:1589–1594
Lin CP, Yeh PT, Chen PF et al (2014) Cataract extraction surgery in patients with uveitis in Taiwan: risk factors and outcomes. J Formos Med Assoc 113:377–384
Kawaguchi T, Mochizuki M, Miyata K, Miyata N (2007) Phacoemulsification cataract extraction and intraocular lens implantation in patients with uveitis. J Cataract Refract Surg 33:305–309
Agrawal R, Murthy S, Ganesh SK et al (2012) Cataract surgery in uveitis. Int J Inflamm 2012:548453
Ram J, Gupta A, Kumar S et al (2010) Phacoemulsification with intraocular lens implantation in patients with uveitis. J Cataract Refract Surg 36:1283–1288
Powe NR, Schein OD, Gieser SC et al (1994) Synthesis of the literature on visual acuity and complications following cataract extraction with intraocular lens implantation. Cataract Patient Outcome Research Team. Arch Ophthalmol 112:239–252
Yamane Cde L, Vianna RN, Cardoso GP et al (2007) Cataract extraction using the phacoemulsification technique in patients with uveitis. Arq Bras Oftalmol 70:683–688
Rahman I, Jones NP (2005) Long-term results of cataract extraction with intraocular lens implantation in patients with uveitis. Eye (London) 19:191–197
Doshi RR, Arevalo JF, Flynn HW Jr, Cunningham ET Jr (2010) Evaluating exaggerated, prolonged, or delayed postoperative intraocular inflammation. Am J Ophthalmol 150:295.e1–304.e1
Jakobsson G, Sundelin K, Zetterberg H, Zetterberg M (2015) Increased levels of inflammatory immune mediators in vitreous from pseudophakic eyes. Investig Ophthalmol Vis Sci 56:3407–3414
Chu L, Wang B, Xu B, Dong N (2013) Aqueous cytokines as predictors of macular edema in non-diabetic patients following uncomplicated phacoemulsification cataract surgery. Mol Vis 19:2418–2425
Estafanous MF, Lowder CY, Meisler DM, Chauhan R (2001) Phacoemulsification cataract extraction and posterior chamber lens implantation in patients with uveitis. Am J Ophthalmol 131:620–625
Kessel L, Tendal B, Jørgensen KJ et al (2014) Post-cataract prevention of inflammation and macular edema by steroid and nonsteroidal anti-inflammatory eye drops: a systematic review. Ophthalmology 121:1915–1924
Wielders LHP, Lambermont VA, Schouten JSAG et al (2015) Prevention of cystoid macular edema after cataract surgery in nondiabetic and diabetic patients: a systematic review and meta-analysis. Am J Ophthalmol 160(968–981):e33
Kim SJ, Schoenberger SD, Thorne JE et al (2015) Topical nonsteroidal anti-inflammatory drugs and cataract surgery: a report by the American Academy Of Ophthalmology. Ophthalmology 122:2159–2168
Dana MR, Chatzistefanou K, Schaumberg DA, Foster CS (1997) Posterior capsule opacification after cataract surgery in patients with uveitis. Ophthalmology 104:1387–1393 (discussion 93-4)
Hewitt A, Verma N (2002) Posterior capsule opacification after cataract surgery in remote Australian Aboriginal patients. Clin Exp Ophthalmol 30:248–251
González N, Quintana JM, Bilbao A et al (2014) Factors affecting cataract surgery complications and their effect on the postoperative outcome. Can J Ophthalmol 49:72–79
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
No conflicting relationship exists for any author.
Rights and permissions
About this article
Cite this article
Balta, O., Sungur, G., Acar, M.A. et al. Long-term results of cataract surgery in patients with anterior uveitis. Int Ophthalmol 38, 1399–1407 (2018). https://doi.org/10.1007/s10792-017-0598-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10792-017-0598-z