Skip to main content
Log in

Dacryoendoscopy-guided transcanalicular intralesional interferon alpha 2b for canalicular squamous papillomas

  • Case Report
  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

Canalicular papillomatosis is a rare disorder characterized by a mass lesion arising from the epithelium as a stalk from one of the canalicular walls. Traditionally, they have been treated with an open canaliculotomy and excision biopsy with or without additional cryotherapy. A patient with upper canalicular squamous papillomas treated with dacryoendoscopy-guided transcanalicular intralesional and topical interferon alpha 2b is presented, and the ineffectiveness of interferons in this case is discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

References

  1. Williams R, Ilsar M, Welham RAN (1985) Lacrimal canalicular papillomatosis. Br J Ophthalmol 69:464–467

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  2. Lass JH, Grove AS, Papale JJ et al (1983) Detection of human papilloma virus DNA. Sequence is conjunctival papilloma. Am J Ophthalmol 96:670–674

    Article  PubMed  CAS  Google Scholar 

  3. Migliori ME, Putterman AM (1990) Recurrent conjunctival papilloma causing nasolacrimal duct obstruction. Am J Ophthalmol 110:17–22

    Article  PubMed  CAS  Google Scholar 

  4. Slade CS, Katz NN, Whitmore PV, Bardenstein DS (1988) Conjunctival and canalicular papillomas and ichthyosis vulgaris. Ann Ophthalmol 20:251–255

    PubMed  CAS  Google Scholar 

  5. Siedlecki AN, Tapp S, Tosteson AN et al (2016) Surgery versus interferon alpha 2b treatment strategies for ocular surface squamous neoplasia: a literature based decision analysis. Cornea 35:613–618

    Article  PubMed  PubMed Central  Google Scholar 

  6. Karp CL, Garol A, Chhabra S et al (2010) Subconjunctival/perilesional recombinant interferon alpha 2b for ocular surface squamous neoplasia: a 10 year review. Ophthalmology 117:2241–2246

    Article  PubMed  Google Scholar 

  7. Bracarda S, Eggermont AM, Samuelsson J (2010) Redefining the role of interferons in the treatment of malignant diseases. Eur J Cancer 46:284–297

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgements

Dr. Ali receives support from the Alexander Von Humboldt foundation for his research and also receives royalties from Springer for the textbook “Principles and Practice of Lacrimal Surgery.” Other authors have none.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mohammad Javed Ali.

Ethics declarations

Conflict of interest

None.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ali, M.J., Singh, S., Ganguly, A. et al. Dacryoendoscopy-guided transcanalicular intralesional interferon alpha 2b for canalicular squamous papillomas. Int Ophthalmol 38, 1343–1346 (2018). https://doi.org/10.1007/s10792-017-0572-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10792-017-0572-9

Keywords

Navigation