Abstract
Canalicular papillomatosis is a rare disorder characterized by a mass lesion arising from the epithelium as a stalk from one of the canalicular walls. Traditionally, they have been treated with an open canaliculotomy and excision biopsy with or without additional cryotherapy. A patient with upper canalicular squamous papillomas treated with dacryoendoscopy-guided transcanalicular intralesional and topical interferon alpha 2b is presented, and the ineffectiveness of interferons in this case is discussed.
References
Williams R, Ilsar M, Welham RAN (1985) Lacrimal canalicular papillomatosis. Br J Ophthalmol 69:464–467
Lass JH, Grove AS, Papale JJ et al (1983) Detection of human papilloma virus DNA. Sequence is conjunctival papilloma. Am J Ophthalmol 96:670–674
Migliori ME, Putterman AM (1990) Recurrent conjunctival papilloma causing nasolacrimal duct obstruction. Am J Ophthalmol 110:17–22
Slade CS, Katz NN, Whitmore PV, Bardenstein DS (1988) Conjunctival and canalicular papillomas and ichthyosis vulgaris. Ann Ophthalmol 20:251–255
Siedlecki AN, Tapp S, Tosteson AN et al (2016) Surgery versus interferon alpha 2b treatment strategies for ocular surface squamous neoplasia: a literature based decision analysis. Cornea 35:613–618
Karp CL, Garol A, Chhabra S et al (2010) Subconjunctival/perilesional recombinant interferon alpha 2b for ocular surface squamous neoplasia: a 10 year review. Ophthalmology 117:2241–2246
Bracarda S, Eggermont AM, Samuelsson J (2010) Redefining the role of interferons in the treatment of malignant diseases. Eur J Cancer 46:284–297
Acknowledgements
Dr. Ali receives support from the Alexander Von Humboldt foundation for his research and also receives royalties from Springer for the textbook “Principles and Practice of Lacrimal Surgery.” Other authors have none.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
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Ali, M.J., Singh, S., Ganguly, A. et al. Dacryoendoscopy-guided transcanalicular intralesional interferon alpha 2b for canalicular squamous papillomas. Int Ophthalmol 38, 1343–1346 (2018). https://doi.org/10.1007/s10792-017-0572-9
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DOI: https://doi.org/10.1007/s10792-017-0572-9